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NCT04581213: PEDICACHE
Effect of Anesthesia Induction on Cerebral Hemodynamic in Children
trial testing General anesthesia in Anesthesia; Reaction in 50 participants. Completed in 24 February 2021.
24 February 2021
Quick facts
| Lead sponsor | St. Justine's Hospital |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 50 |
| Start date | 24 August 2020 |
| Primary completion | 24 February 2021 |
| Estimated completion | 24 February 2021 |
| Sites | 1 location across Canada |
Drugs / interventions tested
- General anesthesia — full drug profile →
Conditions studied
- Anesthesia; Reaction — all drugs for Anesthesia; Reaction →
- Children, Only — all drugs for Children, Only →
Sponsor
St. Justine's Hospital
Who can join
Adults 6 Months to 5, any sex, with Anesthesia; Reaction or Children, Only. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
General anesthesia induces hemodynamic changes, notably a reduction of arterial blood pressure going up to 30%, that may impact cerebral perfusion and oxygenation.The purpose of this study is to assess the impact of anesthesia on the cerebral oxygenation, the perfusion of the brain (assessed with transcranial doppler), and the depth of anesthesia in children between 6 months and 5 years old during the induction of general anesthesia (induced with sevoflurane and/or IV agents). It is expected that the cerebral hemodynamic will be maintained despite systemic variations.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04581213
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of General anesthesia
Trials testing the same drug.
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Other recruiting trials for Anesthesia; Reaction
Currently open trials in the same condition.
- NCT03839784 — Building a Platform for Precision Anesthesia in the Geriatric Surgical Patient · recruiting
- NCT04435834 — Individual Cerebral Hemodynamic Oxygenation Relationships · Phase 4 · recruiting
Other St. Justine's Hospital trials
Trials by the same sponsor.
- NCT04627766 — Validation of Continuous Monitoring of Vital Signs in Children With a Connected Patch · NA · recruiting
- NCT06537622 — Best Practices Fo Early Diagnosis of Cerebral Palsy · NA · not yet recruiting
- NCT06192368 — Virtual Reality Program to Reduce Stress in Neonatal Nurses · NA · completed
- NCT06217510 — Pilot Project on the Automatic Design and 3D Printing of Adolescent Idiopathic Scoliosis Braces (Phase 1) · NA · unknown
- NCT06173102 — Cranial Orthosis Therapy for Plagiocephaly: an RCT Pilot Study Comparing Cranial Orthosis to the Natural Course · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04581213 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by St. Justine's Hospital
- Last refreshed: 3 May 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04581213.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing