Who is sponsoring PAINLESS?

PAINLESS is sponsored by Jerry A. Nick, M.D..

What condition does PAINLESS study?

PAINLESS studies Cystic Fibrosis.

What drugs are being tested in PAINLESS?

Interventions: urine lipoarabinomannan (LAM).

What is the status of PAINLESS?

PAINLESS is currently ENROLLING_BY_INVITATION.

Last reviewed 2025-05-23 · How we verify

Prospective Analysis of Urine LAM to Eliminate NTM Sputum Screening (PAINLESS)

NCT04579211 ENROLLING_BY_INVITATION

This is a prospective, single-center, nonrandomized observational study to investigate the utility of urine lipoarabinomannan (LAM) as a test to identify individuals at very low risk for having a sputum culture positive for Nontuberculous Mycobacteria (NTM). The study is designed to evaluate if a urine test can eliminate the need for obtaining a sputum specimen to screen for NTM in individuals with Cystic Fibrosis (CF). The participants will be asked to provide 3 urine samples either in person or by mail over approximately 3 years. The 3 urine sample requests will be timed to coincide with their usual clinical care and routine sputum collection.

Details

Lead sponsor	Jerry A. Nick, M.D.
Status	ENROLLING_BY_INVITATION
Enrolment	220
Start date	Thu Dec 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time)
Completion	Fri May 01 2026 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

Cystic Fibrosis

Interventions

urine lipoarabinomannan (LAM)

Countries

United States