NCT04576884 is a clinical trial in Cataract, sponsored by Wenzhou Medical University.

Who is sponsoring NCT04576884?

NCT04576884 is sponsored by Wenzhou Medical University.

Is NCT04576884 still recruiting?

NCT04576884 is currently completed. Last updated 6 October 2020.

Last reviewed 2020-10-06 · How we verify

NCT04576884

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Age-Related Changes and Cycloplegia-Induced Differences in the Human Crystalline Lens

Completed Last updated 6 October 2020

What this trial tests

trial in Cataract in 129 participants. Completed in 30 January 2020.

Timeline

1 April 2019

Primary endpoint
31 May 2019

30 January 2020

Quick facts

Lead sponsor	Wenzhou Medical University
Status	Completed
Study type	OBSERVATIONAL
Enrollment	129
Start date	1 April 2019
Primary completion	31 May 2019
Estimated completion	30 January 2020
Sites	1 location across China

Conditions studied

Cataract — all drugs for Cataract →

Sponsor

Wenzhou Medical University

Who can join

Adults 6 to 86, any sex, with Cataract. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The ocular biometric parameters of the human crystalline lens including anterior chamber depth (ACD), lens thickness (LT), radii of curvature of anterior and posterior lens (ALR and PLR), lens equatorial diameter (LED), and lens vault (LV), automatically quantified by the CASIA2 (SS-OCT; Tomey, Nagoya, Japan). Images of iridocorneal angle were obtained using CASIA2 and the Schlemm' s canal (SC) and trabecular meshwork (TM) were quantified manually. Both cycloplegia and non-cycloplegia images were obtained.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Effect of age and cycloplegia on the morphology of the human crystalline lens: swept-source OCT study.
Li Z, Qu W, Huang J, Meng Z, et al · · 2022 · cited 7× · PMID 34016824 · DOI 10.1097/j.jcrs.0000000000000693
The Relationship Between Age and the Morphology of the Crystalline Lens, Ciliary Muscle, Trabecular Meshwork, and Schlemm's Canal: An <i>in vivo</i> Swept-Source Optical Coherence Tomography Study.
Li Z, Meng Z, Qu W, Li X, et al · · 2021 · cited 6× · PMID 34867468 · DOI 10.3389/fphys.2021.763736

Verify or expand the search:

Other recruiting trials for Cataract

Currently open trials in the same condition.

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Other Wenzhou Medical University trials

Trials by the same sponsor.

NCT06905938 — Comparing Monofocal IOLs in Highly Myopic Cataract Patients · not yet recruiting
NCT06892470 — Visual Quality of Cataract Patients with High Myopia After Implantation of Different Intraocular Lenses · active not recruiting
NCT06751342 — Using Psychophysics Methods to Investigate Sensory Dominance After Cataract Surgery · active not recruiting
NCT06707740 — Comparison of the Effect of Capsular Bend on the Rotational Stability Between Two Toric Intraocular Lenses · active not recruiting
NCT06091722 — Quantitative Assessment of Lid Margin Vascularity Using SS-OCTA · unknown

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04576884 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Wenzhou Medical University
Last refreshed: 6 October 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04576884.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing