NCT04574895 is a NA clinical trial of Hematology Review in Venous Thromboembolism, sponsored by Vanderbilt University Medical Center.

Who is sponsoring NCT04574895?

NCT04574895 is sponsored by Vanderbilt University Medical Center.

What drugs are being tested in NCT04574895?

Interventions in NCT04574895: Hematology Review.

What condition does NCT04574895 study?

NCT04574895 studies Venous Thromboembolism, Pediatrics, Deep Vein Thrombosis, Pulmonary Embolism.

Is NCT04574895 still recruiting?

NCT04574895 is currently completed. Last updated 19 December 2023.

Last reviewed 2023-12-19 · How we verify

NCT04574895

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Using a Real-Time Risk Prediction Model to Predict Pediatric Venous Thromboembolism (VTE) Events

Completed NA Last updated 19 December 2023

What this trial tests

NA trial testing Hematology Review in Venous Thromboembolism in 17,427 participants. Completed in 1 December 2023.

Timeline

2 November 2020

Primary endpoint
31 January 2022

1 December 2023

Quick facts

Lead sponsor	Vanderbilt University Medical Center
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	screening
Enrollment	17,427
Start date	2 November 2020
Primary completion	31 January 2022
Estimated completion	1 December 2023
Sites	1 location across United States

Drugs / interventions tested

Hematology Review

Conditions studied

Venous Thromboembolism — all drugs for Venous Thromboembolism →
Pediatrics — all drugs for Pediatrics →
Deep Vein Thrombosis — all drugs for Deep Vein Thrombosis →
Pulmonary Embolism — all drugs for Pulmonary Embolism →

Sponsor

Vanderbilt University Medical Center

Who can join

Adults 0 to 21, any sex, with Venous Thromboembolism or Pediatrics. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The study will evaluate the effectiveness of a novel, real-time risk prediction model for identifying pediatric patients at risk for developing in-hospital blood clots (or venous thromboembolism \[VTE\]) based on data easily extracted from the electronic medical record. The study will assess whether using the risk percentages for developing VTE derived from the model increases the number of high-risk patients screened by the pediatric hematology team, which may may lead to an overall reduction in the number of pediatric VTEs seen at Monroe Carell Jr. Children's Hospital at Vanderbilt.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

A Real-time Risk-Prediction Model for Pediatric Venous Thromboembolic Events.
Walker SC, Creech CB, Domenico HJ, French B, et al · · 2021 · cited 16× · PMID 34011634 · DOI 10.1542/peds.2020-042325
Model-Guided Decision-Making for Thromboprophylaxis and Hospital-Acquired Thromboembolic Events Among Hospitalized Children and Adolescents: The CLOT Randomized Clinical Trial.
Walker SC, French B, Moore RP, Domenico HJ, et al · · 2023 · cited 14× · PMID 37831448 · DOI 10.1001/jamanetworkopen.2023.37789
Use of a real-time risk-prediction model to identify pediatric patients at risk for thromboembolic events: study protocol for the Children's Likelihood Of Thrombosis (CLOT) trial.
Walker SC, French B, Moore R, Domenico HJ, et al · · 2022 · cited 4× · PMID 36273203 · DOI 10.1186/s13063-022-06823-7

Verify or expand the search:

Other recruiting trials for Venous Thromboembolism

Currently open trials in the same condition.

NCT07399977 — Using a Blood Test and Software Tool to Guide Treatment for Venous Thromboembolism · NA · recruiting
NCT06861088 — The Effect of Kinisoquin™ on Thromboembolic Events in Patients With Metastatic or Locally Advanced Pancreatic Cancer · Phase 3 · recruiting
NCT07140523 — A Study to Compare the Efficacy and Safety of SRSD107 and Enoxaparin in Adult Subjects Undergoing TKA · Phase 2 · recruiting
NCT04211181 — CHIPs-VTE Study in Hospitalized Patients to Prevent Hospital-Acquired Venous Thromboembolism · NA · recruiting
NCT06440694 — Colchicine to Quench the Inflammatory Response After Deep Vein Thrombosis (The Conquer-DVT Pilot Trial) · Phase 3 · recruiting

Other Vanderbilt University Medical Center trials

Trials by the same sponsor.

NCT07005037 — Swallowing Impairments in ICU Survivors and Community-Dwelling Adults · not yet recruiting
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NCT07295288 — Botox Injections in Non-Cranial Nerve VII Innervated Muscles for Facial Synkinesis · Phase 4 · not yet recruiting
NCT07431541 — Topical Carboxytherapy Paste Following Microneedling · Phase 1, PHASE2 · not yet recruiting
NCT07224711 — The Impact of Perioperative Lidocaine Infusions on Enhanced Recovery After Non-Cardiac Surgery · Phase 4 · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04574895 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Vanderbilt University Medical Center
Last refreshed: 19 December 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04574895.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing