Last reviewed · How we verify
NCT04572672
Effect of Pursed-Lip Breathing on Blood Pressure and Heart Rate
NA trial testing Non-pharmacologic treatment; Pursed-Lip Breathing Combined with Number Counting in Hypertensive Urgency in 112 participants. Completed in 14 September 2020.
30 June 2020
Quick facts
| Lead sponsor | Khon Kaen University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 112 |
| Start date | 1 September 2019 |
| Primary completion | 30 June 2020 |
| Estimated completion | 14 September 2020 |
| Sites | 1 location across Thailand |
Drugs / interventions tested
- Non-pharmacologic treatment; Pursed-Lip Breathing Combined with Number Counting
Conditions studied
- Hypertensive Urgency — all drugs for Hypertensive Urgency →
Sponsor
Khon Kaen University
Who can join
Adults 18 to 80, any sex, with Hypertensive Urgency. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Hypertensive urgency (HT urgency) is an alarm sign of uncontrolled hypertension. It can be aggravated by nonadherent to medication and psychosocial stress. Mindfulness is beneficial for reducing stress, while deep and slow breathing is effective for blood pressure (BP) lowering. The objective of the study was to assess the effect of pursed-lip breathing with number counting (PLB with NC) that promotes mindfulness and a deep/slow breathing pattern on BP and heart rate (HR) in the HT urgency patients.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
The effect of pursed-lip breathing combined with number counting on blood pressure and heart rate in hypertensive urgency patients: A randomized controlled trial.
Mitsungnern T, Srimookda N, Imoun S, Wansupong S, et al · · 2021 · cited 9× · PMID 33410589 · DOI 10.1111/jch.14168
Verify or expand the search:
- PubMed search for NCT04572672
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Hypertensive Urgency
Currently open trials in the same condition.
- NCT06635603 — HYPERTENSIVE CRISIS AND ATMOSPHERIC PRESSURE RELATIONSHIP · recruiting
Other Khon Kaen University trials
Trials by the same sponsor.
- NCT07494396 — An AI-Based Erythema Measurement System for Psoriasis Lesions · not yet recruiting
- NCT07054775 — Comparison of Pruritus Incidence After Intrathecal Morphine 0.1 vs 0.2 mg in Cesarean Section · Phase 4 · recruiting
- NCT06994520 — Efficacy of Topical Cannabidiol for Eczema · Phase 2 · active not recruiting
- NCT06958029 — Postoperative Atrial Fibrillation in Cardiac Surgery · recruiting
- NCT06289257 — Analysis of Vitamin D and VDR Expression in Endometriosis: A Case-Control Study · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04572672 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Khon Kaen University
- Last refreshed: 1 October 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04572672.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing