NCT04568525

Passive Microwave Radiometry (MWR) and AI for COVID-19 Complications Early Diagnostics of Lungs

Completed NA Last updated 29 September 2020

What this trial tests

NA trial testing Passive Microwave Radiometry in Covid19 in 195 participants. Completed in 1 August 2020.

Timeline

1 July 2020

Primary endpoint
25 July 2020

1 August 2020

Quick facts

Lead sponsor	Kyrgyz State Medical Academy
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	diagnostic
Enrollment	195
Start date	1 July 2020
Primary completion	25 July 2020
Estimated completion	1 August 2020
Sites	1 location across Kyrgyzstan

Drugs / interventions tested

• Passive Microwave Radiometry

Conditions studied

• Covid19 — all drugs for Covid19 →

Sponsor

Kyrgyz State Medical Academy

Who can join

Adults 18 to 75, any sex, with Covid19. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

World Health Organization (WHO) declared COVID-19 it as a global pandemic. It becomes clear that the virus spreading mostly deadly due to limited to access to diagnostics tests and equipment. Traditional radiography and CT remain the main methods of the initial examination of the chest organs. Now, most of the diagnostics has been focused on PCR, chest x-Ray/CT manifestations of COVID-19. However, there are problems with CT due to infection control issues, the inefficiencies introduced in CT room decontamination, and lack of CT availability in LMIC (Low Middle Income Countries). Passive microwave radiometry (MWR) is a cheap, non-radioactive and portable technology. It has already been used for diagnostics of cancer, and other diseases. The investigators have tested if MWR could be used for early diagnostics of pulmonary COVID-19 complications.

This was a randomized controlled trial (195 subjects) to evaluate the effectiveness of diagnostics using MWR in patients with pneumonia caused by COVID-19 while they are in hospitals of Kyrgyzstan, and healthy individuals.

The investigator have measured skin (IR) and internal (MWR) temperature by recording passive electromagnetic radiation through the chest wall in the projection of the lungs at 30 symmetrical points on both sides. Pneumonia and lung damage were diagnosed by X-RAY/CT scan and doctor's final diagnosis (pn+/pn-). COVID-19 was determined by PCR test (covid+/covid-).

Overall, the study suggests that the use of MWR is a convenient and safe method for screening diagnostics in COVID-19 patients with suspected pneumonia. Since MWR is an inexpensive, it will ease the financial burden for both patients and the countries, especially in LMIC

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Passive Microwave Radiometry for the Diagnosis of Coronavirus Disease 2019 Lung Complications in Kyrgyzstan.
   Osmonov B, Ovchinnikov L, Galazis C, Emilov B, et al · · 2021 · cited 10× · PMID 33562419 · DOI 10.3390/diagnostics11020259