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NCT04565197
Convalescent Plasma Therapy for COVID-19 Patients
EARLY_PHASE1 trial testing convalescent plasma in SARS-CoV Infection in 20 participants. Status unknown.
30 December 2020
Quick facts
| Lead sponsor | Lahore General Hospital |
|---|---|
| Phase | EARLY_PHASE1 |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 20 |
| Start date | 1 May 2020 |
| Primary completion | 30 December 2020 |
| Estimated completion | 30 December 2020 |
| Sites | 1 location across Pakistan |
Drugs / interventions tested
- convalescent plasma — full drug profile →
Conditions studied
- SARS-CoV Infection — all drugs for SARS-CoV Infection →
Sponsor
Lahore General Hospital
Who can join
Adults 15 to 80, any sex, with SARS-CoV Infection. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Passive immunization involves the administration of antibodies against a given agent to a susceptible individual for the purpose of preventing or treating an infectious disease due to that agent. A general principle of passive antibody therapy is that it is more effective when used for prophylaxis than for treatment of disease. When used for therapy, antibody is most effective when administered shortly after the onset of symptoms
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
Convalescent plasma or hyperimmune immunoglobulin for people with COVID-19: a living systematic review.
Piechotta V, Iannizzi C, Chai KL, Valk SJ, et al · · 2021 · cited 106× · PMID 34013969 · DOI 10.1002/14651858.cd013600.pub4 -
Convalescent plasma for people with COVID-19: a living systematic review.
Iannizzi C, Chai KL, Piechotta V, Valk SJ, et al · · 2023 · cited 24× · PMID 36734509 · DOI 10.1002/14651858.cd013600.pub5 -
Convalescent plasma for people with COVID-19: a living systematic review.
Iannizzi C, Chai KL, Piechotta V, Valk SJ, et al · · 2023 · cited 21× · PMID 37162745 · DOI 10.1002/14651858.cd013600.pub6
Verify or expand the search:
- PubMed search for NCT04565197
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of convalescent plasma
Trials testing the same drug.
- NCT04388410 — Safety and Efficacy of Convalescent Plasma Transfusion for Patients With COVID-19 · Phase 2, PHASE3 · unknown
- NCT04415086 — Treatment of Patients With COVID-19 With Convalescent Plasma · Phase 2 · completed
- NCT04616976 — COVID-19 With Convalescent Plasma · completed
Other recruiting trials for SARS-CoV Infection
Currently open trials in the same condition.
- NCT05886816 — Mitoquinone/Mitoquinol Mesylate as Oral and Safe Postexposure Prophylaxis for Covid-19 · Phase 2 · recruiting
- NCT04802408 — SARS-Cov-2 (COVID-19) Nasal Pharyngeal and Oral Pharyngeal Wash (SNOW) Trial · Phase 2, PHASE3 · active not recruiting
- NCT04815096 — Imaging Immune Activation in COVID-19 · Phase 2 · recruiting
- NCT04747522 — Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2) Immune Kidney Transplant Study (COVID-19) · active not recruiting
- NCT04579471 — Prevalence and Outcome of SARS-CoV-2 Infection & COVID-19 in Transplant Recipients: The COVITRA Study · recruiting
Other Lahore General Hospital trials
Trials by the same sponsor.
- NCT07470359 — Comparison of Functional Outcomes Following Arthroscopic ACL Reconstruction With Peroneus Longus Autograft With and With · Phase 2 · recruiting
- NCT07261306 — Comparison Between Oral Methotrexate and Tofacitinib in Chronic Plaque Psoriasis · EARLY_PHASE1 · recruiting
- NCT07112898 — Effect of Platelet-Rich Plasma on Graft Uptake and Postoperative Outcomes in Full-Thickness Skin Grafting of Face and Ne · NA · enrolling by invitation
- NCT07478874 — Prophylaxis Against Surgical Site Infections Using Local as Well as Systemic Antibiotic · NA · completed
- NCT07460908 — Comparison of Terlipressin Versus Octreotide in Patients With Hepatorenal Syndrome · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04565197 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Lahore General Hospital
- Last refreshed: 8 December 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04565197.
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