NCT04562688 (CICADAS) is a NA clinical trial of CICADAS only in Autism Spectrum Disorder, sponsored by Posit Science Corporation.

Who is sponsoring NCT04562688?

NCT04562688 is sponsored by Posit Science Corporation.

What drugs are being tested in NCT04562688?

Interventions in NCT04562688: CICADAS only, PEERS + CICADAS and then no-contact, PEERS + Active Comparator and then no-contact.

What condition does NCT04562688 study?

NCT04562688 studies Autism Spectrum Disorder.

Is NCT04562688 still recruiting?

NCT04562688 is currently completed. Last updated 7 February 2025.

Last reviewed 2025-02-07 · How we verify

NCT04562688: CICADAS

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Care Improving Cognition for ADolescents on the Autism Spectrum

Completed NA Last updated 7 February 2025

What this trial tests

NA trial testing CICADAS only in Autism Spectrum Disorder in 68 participants. Completed in 3 November 2023.

Timeline

11 June 2021

Primary endpoint
3 November 2023

3 November 2023

Quick facts

Lead sponsor	Posit Science Corporation
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	triple
Primary purpose	treatment
Enrollment	68
Start date	11 June 2021
Primary completion	3 November 2023
Estimated completion	3 November 2023
Sites	1 location across United States

Drugs / interventions tested

CICADAS only
PEERS + CICADAS and then no-contact
PEERS + Active Comparator and then no-contact

Conditions studied

Autism Spectrum Disorder — all drugs for Autism Spectrum Disorder →

Sponsor

Posit Science Corporation — full company profile →

Who can join

Adults 11 to 18, any sex, with Autism Spectrum Disorder. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This is a validation study to evaluate the acceptability, feasibility and impact of CICADAS (Care Improving Cognition for ADolescents on the Autism Spectrum), a clinician-assisted, digital application that aims to prime the brain to engage in flexible, adaptive long-term learning about social-emotional events through closed-loop technology.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Neuroplasticity-Based Targeted Cognitive Training as Enhancement to Social Skills Program: A Randomized Controlled Trial Investigating a Novel Digital Application for Autistic Adolescents.
Tseng A, Yang A, Van Hecke AV, Hudock RL, et al · · 2026 · PMID 41938232 · DOI 10.1016/j.jaacop.2025.11.003

Verify or expand the search:

Other recruiting trials for Autism Spectrum Disorder

Currently open trials in the same condition.

NCT07324057 — The Effects of Preoperative Intranasal Administration of Dexmedetomidine and Esketamine on Negative Postoperative Behavi · NA · recruiting
NCT07493096 — Intensive Multimodal Neurorehabilitation Targeting Neuroplasticity in Pediatric Neurodevelopmental and Chromosomal Disor · recruiting
NCT07505290 — Efficacy of the Korean PEERS® for Preschoolers (PEERS®-PS-K) Social Skills Intervention: A Randomized Controlled Trial f · NA · active not recruiting
NCT07524192 — A Self-Instructional Online Program for Early Childhood and Elementary Teachers Supporting Autistic Children and Childre · NA · recruiting
NCT07432776 — Effect of an 8-Week Pickleball Program for Adults With Autism: A Feasibility Trial With a Delayed-Control Design · EARLY_PHASE1 · recruiting

Other Posit Science Corporation trials

Trials by the same sponsor.

NCT07243600 — Improving Neurological Health With Acetylcholine Via Neuroplasticity-based Computerized Exercise in Mild Cognitive Impai · NA · not yet recruiting
NCT06589024 — Remote STATE Training for Insomnia in Older Adults · NA · active not recruiting
NCT05599490 — Brain Enhancement Training Towards Elders Resilience to Aging, Phase IIB · NA · completed
NCT05529706 — Community-based Brain Health Program to Address Dementia Risk · NA · completed
NCT05022589 — Remote Digital Health Intervention to Improve Balance and Reduce Fall Risk · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04562688 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Posit Science Corporation
Last refreshed: 7 February 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04562688.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing