Last reviewed · How we verify
NCT04560270
CIrculating Tumor DNA for Monitoring Response to First Line Chemotherapy in Unresectable PANcreatic Cancer
NA trial testing Blood samples in Pancreatic Cancer in 69 participants. Completed in 15 November 2019.
28 June 2019
Quick facts
| Lead sponsor | Poitiers University Hospital |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | diagnostic |
| Enrollment | 69 |
| Start date | 25 April 2016 |
| Primary completion | 28 June 2019 |
| Estimated completion | 15 November 2019 |
Drugs / interventions tested
- Blood samples — full drug profile →
Conditions studied
- Pancreatic Cancer — all drugs for Pancreatic Cancer →
- Circulating Tumor DNA — all drugs for Circulating Tumor DNA →
- KRAS Mutation-Related Tumors — all drugs for KRAS Mutation-Related Tumors →
Sponsor
Poitiers University Hospital
Who can join
18 and older, any sex, with Pancreatic Cancer or Circulating Tumor DNA. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
With an incidence of more than 11,600 new cases per year in France and an annual number of deaths close to the incidence rate, adenocarcinoma of the pancreas is a public health problem. The aim of this study is to assess the predictive value of response to the 1st line of chemotherapy of mutated KRAS ctDNA (circulating tumor DNA) in unresectable metastatic or locally advanced pancreatic adenocarcinomas.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Circulating tumor DNA in unresectable pancreatic cancer is a strong predictor of first-line treatment efficacy: The KRASCIPANC prospective study.
Evrard C, Ingrand P, Rochelle T, Martel M, et al · · 2023 · cited 14× · PMID 37308396 · DOI 10.1016/j.dld.2023.03.011 -
Circulating tumor DNA: toward evolving the clinical paradigm of pancreatic ductal adenocarcinoma.
Topham JT, Renouf DJ, Schaeffer DF. · · 2023 · cited 9× · PMID 36895849 · DOI 10.1177/17588359231157651
Verify or expand the search:
- PubMed search for NCT04560270
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Poitiers University Hospital trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04560270 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Poitiers University Hospital
- Last refreshed: 23 September 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04560270.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing