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NCT04560270

CIrculating Tumor DNA for Monitoring Response to First Line Chemotherapy in Unresectable PANcreatic Cancer

Completed NA Last updated 23 September 2020
What this trial tests

NA trial testing Blood samples in Pancreatic Cancer in 69 participants. Completed in 15 November 2019.

Timeline
25 April 2016
Primary endpoint
28 June 2019
15 November 2019

Quick facts

Lead sponsorPoitiers University Hospital
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationna
Designsingle group
Maskingnone
Primary purposediagnostic
Enrollment69
Start date25 April 2016
Primary completion28 June 2019
Estimated completion15 November 2019

Drugs / interventions tested

Conditions studied

Sponsor

Poitiers University Hospital

Who can join

18 and older, any sex, with Pancreatic Cancer or Circulating Tumor DNA. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

With an incidence of more than 11,600 new cases per year in France and an annual number of deaths close to the incidence rate, adenocarcinoma of the pancreas is a public health problem. The aim of this study is to assess the predictive value of response to the 1st line of chemotherapy of mutated KRAS ctDNA (circulating tumor DNA) in unresectable metastatic or locally advanced pancreatic adenocarcinomas.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Circulating tumor DNA in unresectable pancreatic cancer is a strong predictor of first-line treatment efficacy: The KRASCIPANC prospective study.
    Evrard C, Ingrand P, Rochelle T, Martel M, et al · · 2023 · cited 14× · PMID 37308396 · DOI 10.1016/j.dld.2023.03.011
  2. Circulating tumor DNA: toward evolving the clinical paradigm of pancreatic ductal adenocarcinoma.
    Topham JT, Renouf DJ, Schaeffer DF. · · 2023 · cited 9× · PMID 36895849 · DOI 10.1177/17588359231157651

Verify or expand the search:

Other trials of Blood samples

Trials testing the same drug.

Other recruiting trials for Pancreatic Cancer

Currently open trials in the same condition.

Other Poitiers University Hospital trials

Trials by the same sponsor.

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Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04560270.

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