NCT04559711

cRCT to Improve Maternal Nutrition Service Delivery During ANC

Status unknown NA Last updated 7 April 2022

What this trial tests

NA trial testing Strengthening coverage and quality of nutrition services during ANC in Maternal Nutritional Deficiency During Childbirth in 2,520 participants. Status unknown.

Timeline

1 October 2020

Primary endpoint
31 December 2022

31 December 2022

Quick facts

Lead sponsor	International Centre for Diarrhoeal Disease Research, Bangladesh
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	health services research
Enrollment	2,520
Start date	1 October 2020
Primary completion	31 December 2022
Estimated completion	31 December 2022
Sites	1 location across Bangladesh

Drugs / interventions tested

• Strengthening coverage and quality of nutrition services during ANC

Conditions studied

• Maternal Nutritional Deficiency During Childbirth — all drugs for Maternal Nutritional Deficiency During Childbirth →

Sponsor

International Centre for Diarrhoeal Disease Research, Bangladesh — full company profile →

Who can join

Adults 18 to 49, female only, with Maternal Nutritional Deficiency During Childbirth. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Malnutrition among women of reproductive age is a significant public health problem in Bangladesh, with major implications for a woman's own health and that of her newborn child. The principal drivers for maternal malnutrition in Bangladesh are poor-quality diets, care seeking practices and access to health care. An ideal contact point for pregnant women are antenatal care visits (ANC). However, the provision of maternal nutrition services through government systems is inadequate with just 29% of pregnant women attending all 4 ANC visits and 18% of women consuming at least 100 IFA tablets. Moreover, WHO made a context specific recommendation that countries with a high prevalence of nutritional deficiencies may choose to adopt multiple micronutrient supplementation (MMS) over iron folic acid (IFA). The health benefits of MMS cannot be harnessed without a properly functioning delivery platform. A multifaceted approach focusing on improving the quality of ANC, the supply system for these services, engagement with communities, in addition to the adoption of MMS may have large benefits to women and children in Bangladesh. UNICEF and the Bill and Melinda Gates Foundation have partnered with several different organizations, including the GoB, Sight \& Life, Pennsylvania State University (PSU) and icddr, b to design and assess outcome of a community based randomized control trial to improve coverage and quality of maternal nutrition service delivery through ANC platform. The investigators hypothesize that implementation of demonstration programme will result in 60% relative improvement in the coverage of 100+ MMS among women who received 4+ANC in the intervention areas compared to the coverage of 100+ IFA among women who received 4+ANC in comparison areas.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Iron and Folic Acid Supplementation in Pregnancy: Findings from the Baseline Assessment of a Maternal Nutrition Service Programme in Bangladesh.
   Billah SM, Raynes-Greenow C, Ali NB, Karim F, et al · · 2022 · cited 22× · PMID 35956291 · DOI 10.3390/nu14153114