Last reviewed · How we verify
NCT04557527: VIKING
Suprachoroidal Visco-buckling for the Treatment of Rhegmatogenous Retinal Detachment
NA trial testing Pars plana vitrectomy, laser or cryo retinopexy and intraocular gas tamponade in Retinal Detachment With Break in 36 participants. Completed in 30 April 2025.
31 December 2024
Quick facts
| Lead sponsor | King's College Hospital NHS Trust |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 36 |
| Start date | 7 February 2022 |
| Primary completion | 31 December 2024 |
| Estimated completion | 30 April 2025 |
| Sites | 6 locations across United Kingdom |
Drugs / interventions tested
- Pars plana vitrectomy, laser or cryo retinopexy and intraocular gas tamponade
- Suprachoroidal viscobuckle with 2.3% Sodium hyaluronate (Healon 5 Ophthalmic viscoelastic device)
Conditions studied
- Retinal Detachment With Break — all drugs for Retinal Detachment With Break →
Sponsor
King's College Hospital NHS Trust
Who can join
18 and older, any sex, with Retinal Detachment With Break. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The study compares standard surgery for retinal detachment (RD) (vitrectomy, cryotherapy and gas) with a surgical variation that replaces the intraocular gas tamponade with suprachoroidal injection of viscoelastic underneath the break that caused the retinal detachment.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Human retinal secretome: A cross-link between mesenchymal and retinal cells.
Donato L, Scimone C, Alibrandi S, Scalinci SZ, et al · · 2023 · cited 6× · PMID 37545752 · DOI 10.4252/wjsc.v15.i7.665 -
Suprachoroidal VIsco-bucKlING versus gas tamponade for the treatment of rhegmatogenous retinal detachment (VIKING): study protocol for a multi-centre, randomised, controlled feasibility study.
Saidkasimova S, Lee CN, Murphy GSP, Jackson TL, et al · · 2026 · PMID 41845462 · DOI 10.1186/s40814-026-01787-w
Verify or expand the search:
- PubMed search for NCT04557527
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other King's College Hospital NHS Trust trials
Trials by the same sponsor.
- NCT07384884 — Surgery and Laser Interstitial Thermal Therapy for Bilateral Glioblastomas · NA · not yet recruiting
- NCT07379723 — Brief Intervention for FCD: A Feasibility Study · NA · recruiting
- NCT07062731 — Pelvic Floor Exercises for Suboptimal Anorectal Manometry · recruiting
- NCT06766162 — Virtual Reality to Improve Patient Experience During Endoscopic Mucosal and Submucosal Resection · NA · completed
- NCT06918756 — Development of a Cough Control Questionnaire (CCQ) · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04557527 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by King's College Hospital NHS Trust
- Last refreshed: 6 August 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04557527.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing