The Use of Low Dose Metronidazole to Decrease Postoperative Pain After Endometriosis Surgery: a Prospective, Randomized, Placebo-Controlled Trial

NCT04554693 Phase 4 ACTIVE_NOT_RECRUITING

The purpose of this study is to determine a difference in participant reported pain after endometriosis surgery in participants given oral metronidazole versus placebo.

Details

Lead sponsor	University of Louisville
Phase	Phase 4
Status	ACTIVE_NOT_RECRUITING
Enrolment	90
Start date	2020-10-19
Completion	2027-09

Conditions

• Endometriosis
• Endometriosis-related Pain

Interventions

• Metronidazole Oral
• Placebo

Primary outcomes

• Self-reported pain persistence — 6 weeks postoperatively.
  The outcome of binary, subject pain persistence, assessed as yes or no, will be compared between groups using the Fisher exact test.

Countries

United States