NCT04551872 (RESILIENCE) is a NA clinical trial of Digital weight loss intervention in Obesity, sponsored by Duke University.

Who is sponsoring NCT04551872?

NCT04551872 is sponsored by Duke University.

What drugs are being tested in NCT04551872?

Interventions in NCT04551872: Digital weight loss intervention.

What condition does NCT04551872 study?

NCT04551872 studies Obesity, Cardiovascular Risk Factor.

Is NCT04551872 still recruiting?

NCT04551872 is currently completed. Last updated 24 April 2024.

Last reviewed 2024-04-24 · How we verify

NCT04551872: RESILIENCE

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

RESILIENCE: Personalizing Cardiovascular Health

Completed NA Last updated 24 April 2024

What this trial tests

NA trial testing Digital weight loss intervention in Obesity in 598 participants. Completed in 22 March 2024.

Timeline

22 September 2020

Primary endpoint
22 March 2023

22 March 2024

Quick facts

Lead sponsor	Duke University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	non randomized
Design	parallel
Masking	none
Primary purpose	health services research
Enrollment	598
Start date	22 September 2020
Primary completion	22 March 2023
Estimated completion	22 March 2024
Sites	1 location across United States

Drugs / interventions tested

Digital weight loss intervention

Conditions studied

Obesity — all drugs for Obesity →
Cardiovascular Risk Factor — all drugs for Cardiovascular Risk Factor →

Sponsor

Duke University

Who can join

Adults 40 to 75, any sex, with Obesity or Cardiovascular Risk Factor. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Obesity is a rapidly growing epidemic that is associated with the development of cardiovascular disease (CVD). However, some individuals with obesity appear to be resistant to CVD, and other individuals demonstrate resilience to obesity and CVD risk factors. The investigator's overall objective is to understand factors contributing to the heterogeneity of CVD resistance and resilience among individuals with obesity at Duke.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Design and rationale of the pERSonalized cardIovascuLar dIsease prEvention, treatmeNt, and CarE (RESILIENCE) study.
Rennyson K, Kenjale A, Chiswell K, Li Y, et al · · 2026 · PMID 42248410 · DOI 10.1016/j.cct.2026.108369
Messaging Modality and Content for Recruitment of Research Participants: A Randomized Clinical Trial.
Gouda P, Glover L, Kenjale A, Chiswell K, et al · · 2026 · PMID 42172031 · DOI 10.1001/jamanetworkopen.2026.14046
Audiovisual Augmentation of Electronic Consent to Improve Consent Rates and Comprehension: A Randomized Clinical Trial.
Gouda P, Glover L, Kenjale A, Chiswell K, et al · · 2026 · PMID 42060306 · DOI 10.1001/jamanetworkopen.2026.9347

Verify or expand the search:

Other recruiting trials for Obesity

Currently open trials in the same condition.

NCT07403604 — Effect of Insulin Lowering on Lipogenesis · Phase 1 · recruiting
NCT07509307 — AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee · Phase 3 · recruiting
NCT07272837 — Impact of Semaglutide (Ozempic/Wegovy®) on Heart and Muscle Mass · recruiting
NCT07481630 — A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoart · Phase 3 · recruiting
NCT07527195 — Understanding the Effect of CagriSema, Cagrilintide, and Semaglutide on Muscle Health (Role of Amylin Signature in Muscl · Phase 1 · recruiting

Other Duke University trials

Trials by the same sponsor.

NCT07216456 — Vaginal Dilator Therapy After Pelvic Radiation · NA · not yet recruiting
NCT07519317 — Dosing and Deployment Trial: A Home-based Optokinetic Treatment · NA · not yet recruiting
NCT07275359 — Investigating Senolytic Properties in Pulmonary Rehabilitation and Metformin in COPD Exacerbations · Phase 1 · not yet recruiting
NCT07216963 — The Community Paramedic Response and Overdose Outreach With Supportive Medical-Legal Services Study · NA · not yet recruiting
NCT07459218 — IDEAS for Hope to Reduce Suicide Risk and Improve HIV Care Engagement in Tanzania · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04551872 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Duke University
Last refreshed: 24 April 2024

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04551872.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing