NCT04549935 is a Phase 4 clinical trial of Dextenza in Patient Preference, sponsored by Vance Thompson Vision - MT.

Who is sponsoring NCT04549935?

NCT04549935 is sponsored by Vance Thompson Vision - MT.

What drugs are being tested in NCT04549935?

Interventions in NCT04549935: Dextenza, Topical Prednisolone.

What condition does NCT04549935 study?

NCT04549935 studies Patient Preference, Patient Outcomes, Post-Operative Inflammation, Grade of Post-Operative Cystoid Macular Edema, Rate of Post-Operative Cystoid Macular Edema.

Is NCT04549935 still recruiting?

NCT04549935 is currently recruiting now. Last updated 16 September 2020.

Last reviewed 2020-09-16 · How we verify

NCT04549935

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The PRIME Study: A Randomized, Controlled, Prospective Study

Recruiting now Phase 4 Last updated 16 September 2020

What this trial tests

Phase 4 trial testing Dextenza in Patient Preference in 20 participants. Currently enrolling.

Timeline

14 September 2020

Primary endpoint
27 August 2021

27 August 2021

Quick facts

Lead sponsor	Vance Thompson Vision - MT
Phase	Phase 4
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	double
Primary purpose	treatment
Enrollment	20
Start date	14 September 2020
Primary completion	27 August 2021
Estimated completion	27 August 2021
Sites	1 location across United States

Drugs / interventions tested

Dextenza — full drug profile →
Topical Prednisolone — full drug profile →

Conditions studied

Patient Preference — all drugs for Patient Preference →
Patient Outcomes — all drugs for Patient Outcomes →
Post-Operative Inflammation — all drugs for Post-Operative Inflammation →
Grade of Post-Operative Cystoid Macular Edema — all drugs for Grade of Post-Operative Cystoid Macular Edema →

Sponsor

Vance Thompson Vision - MT — full company profile →

Who can join

Adults 22 to 75, any sex, with Patient Preference or Patient Outcomes. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

To investigate the outcomes of patients undergoing bilateral RLE surgery with treatment of dexamethasone intracanilicular insert compared to topical standard care steroid. Desiged to look at patient preference comparing the insert to drops and will also look at patient outcomes including inflammatin and risk of cystoid macular edema post-operatively.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Deep learning for the prediction of early on-treatment response in metastatic colorectal cancer from serial medical imaging.
Lu L, Dercle L, Zhao B, Schwartz LH. · · 2021 · cited 72× · PMID 34789774 · DOI 10.1038/s41467-021-26990-6

Verify or expand the search:

Other trials of Dextenza

Trials testing the same drug.

NCT04464629 — Assessing the Efficacy and Safety of DEXTENZA in Pseudo Phakic Patients Undergoing Gas Bubble Repair and Laser Following · Phase 4 · terminated
NCT04168112 — Intracanalicular Dexamethasone Insert for Post-Corneal Cross-Linking Inflammation and Pain- The LINK Study · Phase 4 · completed

Other recruiting trials for Patient Preference

Currently open trials in the same condition.

NCT06508697 — CT-Angiography Plaque Characteristics and Events in Deferral Patients by Invasive Fractional Flow Reserve · recruiting
NCT06240260 — TENS Unit for Analgesia During IUD Insertion · NA · recruiting
NCT06376799 — Which Health-care Professional(s) to Talk About Advance Care Planning ? · recruiting
NCT06002113 — Eliciting Informed Goals of Care in Elderly Patients · NA · recruiting
NCT04205916 — A Trial Evaluating Patient Preference of Dropless vs Drops Post Cataract Surgery · Phase 4 · recruiting

Other Vance Thompson Vision - MT trials

Trials by the same sponsor.

NCT05136924 — IIT Assessing OC-01Nasal Spray on Symptoms of DED Following CXL · Phase 2 · unknown

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04549935 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Vance Thompson Vision - MT
Last refreshed: 16 September 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04549935.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing