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NCT04549246
Grid Therapy for Tumors of the Head, Neck, Thorax, Abdomen, Pelvis and Extremities.
trial testing Spatially Fractionated Radiation (GRID) Therapy in Radiation Therapy Complication in 83 participants. Completed in 1 June 2024.
1 June 2024
Quick facts
| Lead sponsor | Mayo Clinic |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 83 |
| Start date | 18 June 2020 |
| Primary completion | 1 June 2024 |
| Estimated completion | 1 June 2024 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Spatially Fractionated Radiation (GRID) Therapy
Conditions studied
- Radiation Therapy Complication — all drugs for Radiation Therapy Complication →
- Tumor Neck — all drugs for Tumor Neck →
- Tumor Abdomen — all drugs for Tumor Abdomen →
Sponsor
Mayo Clinic
Who can join
18 and older, any sex, with Radiation Therapy Complication or Tumor Neck. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study is an observational registry study evaluating the clinical outcomes of grid therapy. Subjects will be screened at outpatient clinic visit appointments and interested qualified subjects will be consented and offered participation in this study. Once consent has been obtained, baseline adverse event and QOL data will be collected and subjects will undergo grid therapy and follow-up at 2-4 weeks (for toxicity), and 3-6 months (for toxicities and radiographic control) then per clinical discretion up to 1 year. Patients will be evaluated according to the physician's standard practice and discretion. Patient data will be drawn from the patients' medical records and reported by means of a web-based electronic data collection (EDC) system. Patients will be considered "on study" until 60 months of observation has occurred, withdrawal of consent, lost to follow-up, or study closure. See below for the clinical visit flowchart for data collected at baseline and standard clinic visits.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Novel unconventional radiotherapy techniques: Current status and future perspectives - Report from the 2nd international radiation oncology online seminar.
Tubin S, Vozenin MC, Prezado Y, Durante M, et al · · 2023 · cited 28× · PMID 36910025 · DOI 10.1016/j.ctro.2023.100605 -
Spatially Fractionated Radiation Therapy in Sarcomas: A Large Single-Institution Experience.
Ahmed SK, Petersen IA, Grams MP, Finley RR, et al · · 2024 · cited 23× · PMID 38495033 · DOI 10.1016/j.adro.2023.101401
Verify or expand the search:
- PubMed search for NCT04549246
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Other Mayo Clinic trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04549246 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Mayo Clinic
- Last refreshed: 30 July 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04549246.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing