NCT04549194 (USOP) is a NA clinical trial of Blood collection in Stress, Psychological, sponsored by Direction Centrale du Service de Santé des Armées.

Who is sponsoring NCT04549194?

NCT04549194 is sponsored by Direction Centrale du Service de Santé des Armées.

What drugs are being tested in NCT04549194?

Interventions in NCT04549194: Blood collection, L-Tyrosine 500 Mg, Psychological questionnaires, Photoplethysmography, Placebo.

What condition does NCT04549194 study?

NCT04549194 studies Stress, Psychological.

Is NCT04549194 still recruiting?

NCT04549194 is currently completed. Last updated 25 November 2022.

Last reviewed 2022-11-25 · How we verify

NCT04549194: USOP

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Contribution of L-Tyrosine to Recovery From Operational Strain on Return From External Operation

Completed NA Last updated 25 November 2022

What this trial tests

NA trial testing Blood collection in Stress, Psychological in 116 participants. Completed in 30 June 2021.

Timeline

9 September 2020

Primary endpoint
30 June 2021

30 June 2021

Quick facts

Lead sponsor	Direction Centrale du Service de Santé des Armées
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	prevention
Enrollment	116
Start date	9 September 2020
Primary completion	30 June 2021
Estimated completion	30 June 2021
Sites	1 location across France

Drugs / interventions tested

Blood collection — full drug profile →
L-Tyrosine 500 Mg — full drug profile →
Psychological questionnaires
Photoplethysmography
Placebo

Conditions studied

Stress, Psychological — all drugs for Stress, Psychological →

Sponsor

Direction Centrale du Service de Santé des Armées — full company profile →

Who can join

Adults 18 to 65, any sex, with Stress, Psychological. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Operational conditions amplify soldier's constraints and stress factors, upsetting individual and collective adaptive landmarks. The soldier's resistance is strained by the high intensity of stressors, by the long duration of exposure and by their cumulative effect. This may lead to a state of "operational strain" that refers to chronic stress and the allostatic load imposed by operational constraint. The investigators believe that operational strain could manifest itself by a kind of accelerated aging of the organism due to the increased allostatic load without sufficient resource restoration (neurotransmitter precursors, partial and repeated sleep deprivation, etc.). This aging mechanism would be reversible after a sufficient period of resource restoration (sleep, physical activity, adapted diet, etc.).

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other trials of Blood collection

Trials testing the same drug.

NCT07134491 — Peripheral and Intrarenal B Cell Study in Antibody Mediated Transplant Rejection : Phenotypic and Transcriptional Study, · recruiting
NCT07075107 — Transcriptomic Analysis of Fibroblasts and Blood in Patients With Rare Diseases · NA · not yet recruiting
NCT06510868 — Evaluating Myelodysplastic Syndrome Risks in NET Patients Planned for Peptide Radionuclide Therapy · recruiting
NCT06521502 — The APS Phenotyping Study · recruiting
NCT06373510 — Longitudinal Evaluation of Antibody Kinetics of Vaccinated Patients With Non-mandatory Vaccine Following Administration · NA · not yet recruiting

Other recruiting trials for Stress, Psychological

Currently open trials in the same condition.

NCT07522944 — AI-Guided Relaxation for Hemodialysis Anxiety · NA · recruiting
NCT07255365 — Virtual Reality-Based 360° Clinic Walkthrough for Reducing Examination Anxiety in Preschool Children · NA · recruiting
NCT07313735 — The Effect of Cartoon Character-Printed Band Use During Burn Dressing on Fear, Stress, Pain, and Physiological Parameter · NA · recruiting
NCT06899308 — Health Surveillance at Constructor University Bremen (CUB) and Among HAW-Hamburg Employees · recruiting
NCT06771167 — Building Community Resilience Program · NA · recruiting

Other Direction Centrale du Service de Santé des Armées trials

Trials by the same sponsor.

NCT07352904 — Exploration Strategies in Night Vision Sensors · not yet recruiting
NCT07344493 — Average ANKLE GO Score in the Objective Functional Assessment of the Ankle in Healthy Military Personnel (ANKMIL) · completed
NCT06996275 — Attachment and Post-Traumatic Stress Disorder in Military Personnel: Characterization of the French Military Population, · not yet recruiting
NCT06490029 — Diagnostic of Various Ototoxicity Induced by Cancer Treatment · recruiting
NCT06174181 — Preventive TREatment of Dry Eye in Patients Receiving Repeated Intravitreal Injections for Age-related Macular Degenerat · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04549194 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Direction Centrale du Service de Santé des Armées
Last refreshed: 25 November 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04549194.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing