Who is sponsoring NCT04545931?

NCT04545931 is sponsored by Cairo University.

What drugs are being tested in NCT04545931?

Interventions in NCT04545931: Posterior tibial nerve stimulation, Desmopressin Acetate.

What condition does NCT04545931 study?

NCT04545931 studies Primary Monosymptomatic Nocturnal Enuresis.

Is NCT04545931 still recruiting?

NCT04545931 is currently status unknown. Last updated 11 September 2020.

Last reviewed 2020-09-11 · How we verify

NCT04545931: PTNS

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Posterior Tibial Nerve Stimulation Vs Desmopressin In Children With Primary Monosymptomatic Nocturnal Enuresis

Status unknown Phase 4 Last updated 11 September 2020

What this trial tests

Phase 4 trial testing Posterior tibial nerve stimulation in Primary Monosymptomatic Nocturnal Enuresis in 80 participants. Status unknown.

Timeline

15 March 2020

Primary endpoint
15 November 2020

15 December 2020

Quick facts

Lead sponsor	Cairo University
Phase	Phase 4
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	80
Start date	15 March 2020
Primary completion	15 November 2020
Estimated completion	15 December 2020
Sites	1 location across Egypt

Drugs / interventions tested

Posterior tibial nerve stimulation
Desmopressin Acetate — full drug profile →

Conditions studied

Primary Monosymptomatic Nocturnal Enuresis — all drugs for Primary Monosymptomatic Nocturnal Enuresis →

Sponsor

Cairo University

Who can join

Adults 5 to 12, any sex, with Primary Monosymptomatic Nocturnal Enuresis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Nocturnal enuresis is a worldwide health problem frequently encountered in childhood . It affects 18 % of younger school- age children in Egypt. It is the most frequent (85%) type of enuresis in children (Eberdt-Gołabek et al, 2013), . Nocturnal enuresis includes monosymptomatic nocturnal enuresis with no day time urinary symptoms and non monosymptomatic nocturnal enuresis that accompanied by day time urinary symptoms . It can cause severe psychological and social distress to children and their parents . The currently recommended treatment such as alarms , antidiuretic hormone and anticholenergics are not effective in all children with significant relapse rate . Although it's mechanism of action is not fully elucidated , posterior tibial nerve stimulation is safe and acceptable, with evidence of potential clinical effect for both bladder and bowel dysfunction (Bellette et al, 2009). This study will investigate the effect of posterior tibial nerve stimulation on primary monosymptomatic nocturnal enuresis in children.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Posterior tibial nerve stimulation versus desmopressin in treating children with primary mono-symptomatic nocturnal enuresis. A randomized clinical trial.
Abdelghany M, Amar MS, Shoukry AI, Morsi H, et al · · 2024 · cited 1× · PMID 39355791 · DOI 10.1080/20905998.2024.2373404

Verify or expand the search:

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04545931 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Cairo University
Last refreshed: 11 September 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04545931.

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