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NCT04541966

What Happens to First Trimester Nuchal Translucency

Completed Last updated 10 September 2020
What this trial tests

trial in Nuchal Translucency in 230 participants. Completed in 1 September 2020.

Timeline
1 May 2020
Primary endpoint
1 May 2020
1 September 2020

Quick facts

Lead sponsorUniversity Hospital, Montpellier
StatusCompleted
Study typeOBSERVATIONAL
Enrollment230
Start date1 May 2020
Primary completion1 May 2020
Estimated completion1 September 2020
Sites1 location across France

Conditions studied

Sponsor

University Hospital, Montpellier

Who can join

Eligibility, female only, with Nuchal Translucency. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

First trimester nuchal translucency is a call point for genetic abnormalities and birth defects. Nuchal translucency varies with LCC and therefore with gestational age as described by Chung et al who created a 99th percentile curve of nuchal translucency versus LCC. The majority of centers use the 3.5 mm cutoff as the 99th percentile instead of using nuchal translucency based on LCC. The objective of this study is to compare the fate of nuchal hyperclites\> = 99th p but \<3.5mm versus 3.5mm. For this the investigators have studied the ultrasound and genetic abnormalities. The investigators were also interested in the pregnancy outcomes and the percentage of pregnancies in the group\> = 99th p and \<3.5mm that would have been sampled for a high combined risk for trisomy 21, and therefore to determine the benefit of a systematic sample. for HCN as well as the interest of performing an ACPA that would not be performed on a sample with a high risk of trisomy 21.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

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Other University Hospital, Montpellier trials

Trials by the same sponsor.

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Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04541966.

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