NCT04534504

Sleeve Gastrectomy With Uncut Jejunal Bypass (SG-uncut JJB) Verus Sleeve Gastrectomy in Obese Patients

Status unknown NA Last updated 1 September 2020

What this trial tests

NA trial testing SG-JJB in Excessive Weight Loss in 60 participants. Status unknown.

Timeline

26 August 2020

Primary endpoint
31 August 2022

31 August 2022

Quick facts

Lead sponsor	Zhen Jun Wang
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	60
Start date	26 August 2020
Primary completion	31 August 2022
Estimated completion	31 August 2022
Sites	1 location across China

Drugs / interventions tested

• SG-JJB

Conditions studied

• Excessive Weight Loss — all drugs for Excessive Weight Loss →
• Total Weight Loss — all drugs for Total Weight Loss →
• Sleeve Gastrectomy — all drugs for Sleeve Gastrectomy →
• Jejunojejunal Bypass — all drugs for Jejunojejunal Bypass →

Sponsor

Zhen Jun Wang

Who can join

Adults 16 to 65, any sex, with Excessive Weight Loss or Total Weight Loss. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Among various bariatric procedures, sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB) are the most frequently performed procedures worldwide. Though SG provides similar weight loss effect to RYGB in short-term follow-up, its long-term and very long-term weight loss effect was reported to be inferior to RYGB. Weight regain after SG remains the major concern after 2-year follow-up due to gradual loss of appetite suppression and lack of malabsorption function. SG plus procedures have been developed to strengthen the effect of SG on diabetes control. It has been reported that SG plus jejunojejunal bypass (SG - JJB) offered better weight loss than SG and similar weight loss to RYGB. The present study aims to evaluate the efficacy and safety of sleeve gastrectomy plus uncut jejunojejunal bypass (SG - uncut JJB).

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

1. Short-term outcomes of sleeve gastrectomy plus uncut jejunojejunal bypass (SG-uncut JJB) in patients with obesity: a preliminary prospective cohort study.
   Zhang H, Zhai Z, Cao K, Li G, et al · · 2023 · PMID 36602593 · DOI 10.1007/s00423-022-02742-y
2. [Short-term efficacy of laparoscopic sleeve gastrectomy plus uncut jejunojejunostomy (SG-uncut JJB) for treatment of obesity: a prospective study].
   Li GB, Zhai ZW, Zhang HY, Cao K, et al · · 2022 · PMID 36245116 · DOI 10.3760/cma.j.cn441530-20211231-00539