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NCT04533841
Propranolol and Misoprostol Versus Misoprostol Alone for Induction of Labor in Primigravidas
Phase 2 trial testing Misoprostol in Induction of Labor Affected Fetus / Newborn in 128 participants. Completed in 15 September 2020.
13 September 2020
Quick facts
| Lead sponsor | Ahmed mohamed fathy ismail |
|---|---|
| Phase | Phase 2 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | treatment |
| Enrollment | 128 |
| Start date | 1 February 2020 |
| Primary completion | 13 September 2020 |
| Estimated completion | 15 September 2020 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Misoprostol (Misoprostol) — full drug profile →
- Placebo
- Propranolol (propranolol) — full drug profile →
Conditions studied
- Induction of Labor Affected Fetus / Newborn — all drugs for Induction of Labor Affected Fetus / Newborn →
Sponsor
Ahmed mohamed fathy ismail
Who can join
Adults 18 to 45, female only, with Induction of Labor Affected Fetus / Newborn. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
To compare propranolol and misoprostol versus misoprostol alone for induction of labour in primigravidas
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
A pilot study to compare propranolol and misoprostol versus misoprostol and placebo for induction of labor in primigravidae; a randomized, single-blinded, placebo-controlled trial.
Abdel Hamid AS, Abdel Hamid AS, El Zeneiny H, Fathy A, et al · · 2023 · cited 3× · PMID 37016326 · DOI 10.1186/s12884-023-05537-1
Verify or expand the search:
- PubMed search for NCT04533841
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Misoprostol
Trials testing the same drug.
- NCT07353281 — Carbetocin vs Misoprostol for Postpartum Hemorrhage Prevention · NA · not yet recruiting
- NCT06669533 — Use Misoprostol to Optimize Prevention of Cervical Cancer · NA · recruiting
- NCT07416487 — Comparison of Outcome of Foley Catheter Versus Misoprostol for Induction of Labor · NA · completed
- NCT06765473 — Comparison Between Preoperative Vaginal and Postoperative Sublingual Misoprostol for Prevention of Postpartum Hemorrhage · Phase 3 · not yet recruiting
- NCT06452719 — Letrozole and Misoprostol for Early Pregnancy Loss Management · Phase 2 · recruiting
Other recruiting trials for Induction of Labor Affected Fetus / Newborn
Currently open trials in the same condition.
- NCT06375746 — The Impact of a Customized Informative Video Prior to Induction of Labor on Anxiety Relieve. · NA · recruiting
- NCT06325007 — Castor Oil Ingestion and Balloon Catheter for Labor Induction in Nulliparous · NA · recruiting
- NCT06187779 — Induction ATAD Catheter and Lower Segment Thickness · NA · active not recruiting
- NCT05759988 — Cervical Ripening as an Outpatient Method Using the Foley (COMFORT) · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04533841 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Ahmed mohamed fathy ismail
- Last refreshed: 31 August 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04533841.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing