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NCT04531319
Immune Cell Subgroups in Covid 19 Patients
trial testing Flow cytometric analysis in Covid19 in 50 participants. Completed in 1 October 2020.
1 October 2020
Quick facts
| Lead sponsor | Istanbul Training and Research Hospital |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 50 |
| Start date | 15 August 2020 |
| Primary completion | 1 October 2020 |
| Estimated completion | 1 October 2020 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Flow cytometric analysis
Conditions studied
- Covid19 — all drugs for Covid19 →
Sponsor
Istanbul Training and Research Hospital
Who can join
Adults 18 to 80, any sex, with Covid19. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
COVID-19, spreading rapidly all over the world, causes serious morbidity and mortality. In severe COVID-19 infections, after pulmonary inflammation, cardiovascular organ failure, cytokine storm, hemophagocytosis, septic shock, develops due to uncontrolled hypoxia, and isolated organ failure turns into multi-organ failure. It is noteworthy that it causes lymphopenia in patients. In studies conducted, the effects of Covid-19 on the immune system were evaluated with limited parameters. In addition, no study evaluating the effect of this disease on the immune system has been published in our country.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Natural killer cells in COVID-19: from infection, to vaccination and therapy.
Zafarani A, Razizadeh MH, Pashangzadeh S, Amirzargar MR, et al · · 2023 · cited 24× · PMID 36936055 · DOI 10.2217/fvl-2022-0040 -
The phase I RELEASE clinical trial to evaluate the safety of NK cells in COVID-19.
Hernández-Blanco C, Al-Akioui-Sanz K, Herrera L, Aguirre-Portolés C, et al · · 2025 · cited 1× · PMID 39877904 · DOI 10.1016/j.isci.2024.111698
Verify or expand the search:
- PubMed search for NCT04531319
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Flow cytometric analysis
Trials testing the same drug.
- NCT04531345 — Cytokine Status of Covid-19 Patients · completed
- NCT04566848 — The Status of Immune Checkpoints at Gastrointestinal Cancer · completed
Other recruiting trials for Covid19
Currently open trials in the same condition.
- NCT03305341 — Proof-of-Concept Clinical Pharmacology Trial for COVID-19 Antigen Presentation Therapeutic Biologic Mix · EARLY_PHASE1 · active not recruiting
- NCT06482138 — Dysfunction of Olfaction After COVID-19 Infection: Morphological and Histomolecular Investigation · NA · recruiting
- NCT04924803 — Community Developed Technology-Based Messaging to Increase COVID-19 Vaccine Uptake Among People Who Inject Drugs · NA · active not recruiting
- NCT05013632 — COVID-19 International Drug Pregnancy Registry · recruiting
- NCT04806061 — Urine Alkalinisation in COVID-19 · NA · active not recruiting
Other Istanbul Training and Research Hospital trials
Trials by the same sponsor.
- NCT07499713 — Association of Serum VEGF-A and VCAM-1 Levels With Nailfold Capilleroscopic Alterations in Alopecia Areata · enrolling by invitation
- NCT07335822 — The Effectiveness of Low-Level Laser Therapy in the Treatment of Meralgia Paresthetica · NA · recruiting
- NCT07363187 — Nailfold Capillaroscopy and Endothelial Biomarkers in Healthcare Workers Exposed to Chronic Low-Dose Ionizing Radiation · not yet recruiting
- NCT07415291 — CNN-Based AI Versus Physicians for Solitary Skin Lesion Diagnosis · active not recruiting
- NCT07150702 — Effects of Close Follow-up on Patients With Low Back Pain · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04531319 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Istanbul Training and Research Hospital
- Last refreshed: 12 January 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04531319.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing