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NCT04530500
COVID-19 In-vitro Diagnostic Test and Androgen Receptor Gene Expression
trial testing COVID-19 Androgen Sensitivity Test (CoVAST) in Covid19. Withdrawn.
1 December 2021
Quick facts
| Lead sponsor | University of California, Irvine |
|---|---|
| Status | Withdrawn |
| Study type | OBSERVATIONAL |
| Start date | 13 August 2020 |
| Primary completion | 1 December 2021 |
| Estimated completion | 1 December 2023 |
| Sites | 2 locations across United States |
Drugs / interventions tested
- COVID-19 Androgen Sensitivity Test (CoVAST)
Conditions studied
- Covid19 — all drugs for Covid19 →
- Androgen Receptor Gene Overexpression — all drugs for Androgen Receptor Gene Overexpression →
Sponsor
University of California, Irvine
Who can join
Adults 18 to 90, male only, with Covid19 or Androgen Receptor Gene Overexpression. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This research study will evaluate the association of Androgen Receptor (AR) gene expression and COVID-19 disease severity and mortality. The research procedure involves collection of a single saliva sample which will be mailed to the participants by the study team. This saliva will be used in a COVID-19 Androgen Sensitivity Test (CoVAST) which will detect AR gene expression. Eligible participants are males, at least 18 years or older, and have tested positive for COVID-19.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
An overview of Betacoronaviruses-associated severe respiratory syndromes, focusing on sex-type-specific immune responses.
Rahimi G, Rahimi B, Panahi M, Abkhiz S, et al · · 2021 · cited 21× · PMID 33440306 · DOI 10.1016/j.intimp.2021.107365 -
Protective trend of anti-androgen therapy during the COVID-19 pandemic: A meta-analysis.
Meng J, Ge Q, Li J, Lu X, et al · · 2022 · cited 5× · PMID 35341831 · DOI 10.1016/j.jinf.2022.03.020
Verify or expand the search:
- PubMed search for NCT04530500
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other University of California, Irvine trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04530500 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of California, Irvine
- Last refreshed: 8 May 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04530500.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing