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NCT04530097
Radiofrequency Ablation Combined With Melatonin in the Treatment of Stage IA NSCLC
NA trial testing RFA in NSCLC and Theropy in 260 participants. Status unknown.
30 September 2022
Quick facts
| Lead sponsor | Shanghai 10th People's Hospital |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | treatment |
| Enrollment | 260 |
| Start date | 1 January 2021 |
| Primary completion | 30 September 2022 |
| Estimated completion | 30 September 2022 |
| Sites | 1 location across China |
Drugs / interventions tested
- RFA
Conditions studied
- NSCLC and Theropy — all drugs for NSCLC and Theropy →
Sponsor
Shanghai 10th People's Hospital
Who can join
Adults 18 to 85, any sex, with NSCLC and Theropy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Based on the recommendations of the guidelines, as well as the previous animal studies and clinical studies of our team, we designed and carried out prospective, randomized controlled, double-blind clinical studies to further expand the sample size to verify the efficacy of radiofrequency ablation combined with melatonin in the treatment of stage IA NSCLC. It is hoped that this combined treatment plan can delay the recurrence of lung cancer after RFA and prolong the survival time of patients.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Systematic and comprehensive insights into HIF-1 stabilization under normoxic conditions: implications for cellular adaptation and therapeutic strategies in cancer.
Zhang J, Yao M, Xia S, Zeng F, et al · · 2025 · cited 63× · PMID 39757165 · DOI 10.1186/s11658-024-00682-7
Verify or expand the search:
- PubMed search for NCT04530097
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Shanghai 10th People's Hospital trials
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04530097 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Shanghai 10th People's Hospital
- Last refreshed: 28 August 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04530097.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing