NCT04529473 is a NA clinical trial of Eubacterium hallii in Pre Diabetes, sponsored by Atlantia Food Clinical Trials.

Who is sponsoring NCT04529473?

NCT04529473 is sponsored by Atlantia Food Clinical Trials.

What drugs are being tested in NCT04529473?

Interventions in NCT04529473: Eubacterium hallii, Placebo.

What condition does NCT04529473 study?

NCT04529473 studies Pre Diabetes, Impaired Glucose Tolerance, Insulin Sensitivity, Insulin Resistance, Glucose Metabolism Disorders, Metabolic Syndrome.

Is NCT04529473 still recruiting?

NCT04529473 is currently completed. Last updated 15 November 2022.

Last reviewed 2022-11-15 · How we verify

NCT04529473

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Efficacy and Safety of 12-weeks Supplementation of Eubacterium Hallii on Insulin Sensitivity and Glycaemic Control

Completed NA Last updated 15 November 2022

What this trial tests

NA trial testing Eubacterium hallii in Pre Diabetes in 100 participants. Completed in 23 August 2022.

Timeline

3 February 2021

Primary endpoint
23 August 2022

23 August 2022

Quick facts

Lead sponsor	Atlantia Food Clinical Trials
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	prevention
Enrollment	100
Start date	3 February 2021
Primary completion	23 August 2022
Estimated completion	23 August 2022
Sites	3 locations across United Kingdom, Ireland, United States

Drugs / interventions tested

Eubacterium hallii
Placebo

Conditions studied

Pre Diabetes — all drugs for Pre Diabetes →
Impaired Glucose Tolerance — all drugs for Impaired Glucose Tolerance →
Insulin Sensitivity — all drugs for Insulin Sensitivity →
Insulin Resistance — all drugs for Insulin Resistance →

Sponsor

Atlantia Food Clinical Trials — full company profile →

Who can join

Adults 21 to 69, any sex, with Pre Diabetes or Impaired Glucose Tolerance. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This 12 week placebo-controlled study evaluates the efficacy and safety of E. hallii supplementation.

Publications & conference data

4 peer-reviewed publications reference this trial (live from Europe PMC):

The Role of Next-Generation Probiotics in Obesity and Obesity-Associated Disorders: Current Knowledge and Future Perspectives.
Vallianou NG, Kounatidis D, Tsilingiris D, Panagopoulos F, et al · · 2023 · cited 73× · PMID 37047729 · DOI 10.3390/ijms24076755
<i>Lachnospiraceae</i> are emerging industrial biocatalysts and biotherapeutics.
Zaplana T, Miele S, Tolonen AC. · · 2023 · cited 57× · PMID 38239921 · DOI 10.3389/fbioe.2023.1324396
Next Generation Probiotics for Neutralizing Obesogenic Effects: Taxa Culturing Searching Strategies.
López-Moreno A, Acuña I, Torres-Sánchez A, Ruiz-Moreno Á, et al · · 2021 · cited 21× · PMID 34065873 · DOI 10.3390/nu13051617
<i>Anaerobutyricum soehngenii</i> improves glycemic control and other markers of cardio-metabolic health in adults at risk of type 2 diabetes.
Attaye I, Bird JK, Nieuwdorp M, Gül S, et al · · 2025 · cited 5× · PMID 40371708 · DOI 10.1080/19490976.2025.2504115

Verify or expand the search:

Other recruiting trials for Pre Diabetes

Currently open trials in the same condition.

NCT07252700 — Preventing Diabetes: Impact of an EMR-Based Intervention for Enhanced Pre-Diabetes Management in Primary Care · NA · recruiting
NCT06986161 — Optimizing Mango's Glycemic Impact: Investigating Mango Consumption Timing in Prediabetic Individuals · NA · recruiting
NCT06426277 — Effectiveness of the Brazilian Diabetes Prevention Program · NA · recruiting
NCT06387797 — Primary and Secondary Prevention of Type 2 Diabetes Mellitus in Clark County · NA · recruiting
NCT06555952 — MegaNatural BP® GSE on Blood Pressure and Cardiometabolic Risk Factors · NA · recruiting

Other Atlantia Food Clinical Trials trials

Trials by the same sponsor.

NCT05711303 — Study to Investigate the Effect of Superba Boost on the Skin · NA · completed
NCT03548363 — Effect of Gingest on Symptoms of Dyspepsia · NA · completed
NCT03703024 — An Intervention Study Evaluating the Effects of a Raspberry Leaf Extract in an Osteoarthritic Population. · NA · completed
NCT03083600 — Effect of Protein Hydrolysates on HbA1c Levels in Pre-diabetics · NA · terminated

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04529473 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Atlantia Food Clinical Trials
Last refreshed: 15 November 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04529473.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing