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NCT04529161: FMD1
Olfactory and Taste Changes During Fasting Mimicking Diet (FMD)
NA trial testing Fasting Mimicking Diet (FMD) in Diet, Healthy in 102 participants. Completed in 30 October 2022.
30 October 2022
Quick facts
| Lead sponsor | Uniter Onlus |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | quadruple |
| Primary purpose | supportive care |
| Enrollment | 102 |
| Start date | 1 October 2020 |
| Primary completion | 30 October 2022 |
| Estimated completion | 30 October 2022 |
| Sites | 1 location across Italy |
Drugs / interventions tested
- Fasting Mimicking Diet (FMD)
- Routinary diet habits
Conditions studied
- Diet, Healthy — all drugs for Diet, Healthy →
- Obesity — all drugs for Obesity →
- Olfaction Disorders — all drugs for Olfaction Disorders →
Sponsor
Uniter Onlus
Who can join
Adults 18 to 70, any sex, with Diet, Healthy or Obesity. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Literature experiences demonstrated the impact of medically-assisted pulsed fasting on olfactory behavior in both the animal and human models and - conversely - the lack of homogeneous results linked - up to now - to administrations of pulsed fasting which are not widely codified. Thus, objective of this study protocol is to evaluate the olfactory-gustatory aspects and blood patterns of a group of subjects suffering from obesity / overweight after a 6-month period of Fasting Mimicking Diet (FMD) (Group A) - consisting of a caloric restriction regimen - compared to a group of homogeneous subjects observing their own eating habits (Group B) which - according to a "cross-over" model - will undergo FMD in the following semester during which the subjects belonging to Group A will observe their eating habits.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Chemosensory and cardiometabolic improvements after a fasting-mimicking diet: A randomized cross-over clinical trial.
Micarelli A, Mrakic-Sposta S, Vezzoli A, Malacrida S, et al · · 2025 · cited 1× · PMID 39970875 · DOI 10.1016/j.xcrm.2025.101971
Verify or expand the search:
- PubMed search for NCT04529161
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Fasting Mimicking Diet (FMD)
Trials testing the same drug.
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Other recruiting trials for Diet, Healthy
Currently open trials in the same condition.
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- NCT07027865 — Sip and Snack Better (SSB) Study: Improving Added Sugar in Adolescents · NA · active not recruiting
- NCT06932666 — Why Calories Are Not the Same - a Gut Explanation? · NA · active not recruiting
- NCT07221045 — A Food As Medicine Approach to Address Food Insecurity in Rural North Carolina · NA · recruiting
Other Uniter Onlus trials
Trials by the same sponsor.
- NCT07053176 — Impact of Local Lidocaine Paravertebral Cervical Injection on Cervicogenic Dizziness Symptoms · Phase 4 · enrolling by invitation
- NCT05174104 — Metabolic and Chronobiological Changes in Vestibular Rehabilitation · NA · completed
- NCT04347148 — Postural and Clinical Outcomes of SNAGs Treatment in Cervicogenic Dizziness Patients: a Randomised Controlled Trial · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04529161 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Uniter Onlus
- Last refreshed: 12 March 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04529161.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing