NCT04525443 is a clinical trial in COVID-19, sponsored by Hospital San Carlos, Madrid.

Who is sponsoring NCT04525443?

NCT04525443 is sponsored by Hospital San Carlos, Madrid.

Is NCT04525443 still recruiting?

NCT04525443 is currently completed. Last updated 26 February 2021.

Last reviewed 2021-02-26 · How we verify

NCT04525443

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Endothelial Function and COVID-19

Completed Last updated 26 February 2021

What this trial tests

trial in COVID-19 in 110 participants. Completed in 11 February 2021.

Timeline

3 June 2020

Primary endpoint
11 November 2020

11 February 2021

Quick facts

Lead sponsor	Hospital San Carlos, Madrid
Status	Completed
Study type	OBSERVATIONAL
Enrollment	110
Start date	3 June 2020
Primary completion	11 November 2020
Estimated completion	11 February 2021
Sites	2 locations across United States, Spain

Conditions studied

COVID-19 — all drugs for COVID-19 →

Sponsor

Hospital San Carlos, Madrid

Who can join

Eligibility, any sex, with COVID-19. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The present study aims to investigate the endothelial vasodilator function in patients with COVID-19

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Epidemiology and organ specific sequelae of post-acute COVID19: A narrative review.
Korompoki E, Gavriatopoulou M, Hicklen RS, Ntanasis-Stathopoulos I, et al · · 2021 · cited 102× · PMID 33992686 · DOI 10.1016/j.jinf.2021.05.004
In-vivo evidence of systemic endothelial vascular dysfunction in COVID-19.
Mejia-Renteria H, Travieso A, Sagir A, Martínez-Gómez E, et al · · 2021 · cited 42× · PMID 34706286 · DOI 10.1016/j.ijcard.2021.10.140
Endothelial dysfunction in COVID-19: A potential predictor of long-COVID?
Seitz A, Ong P. · · 2022 · cited 16× · PMID 34838682 · DOI 10.1016/j.ijcard.2021.11.051

Verify or expand the search:

Other recruiting trials for COVID-19

Currently open trials in the same condition.

NCT07183709 — Safety and Immunogenicity Trial of PepGNP-COVID19 Vaccine in Adults · Phase 1 · active not recruiting
NCT07300839 — A Study to Learn About a COVID-19 Vaccine in Healthy Adults 50 Through 64 Years of Age · Phase 3 · active not recruiting
NCT07221162 — A Safety and Immunogenicity Trial of Boost-2867 Vaccine, Via Intranasal and Intramuscular Routes · Phase 1 · recruiting
NCT07215520 — Safety and Tolerability of a Newcastle Disease Virus-Based Mucosal COVID-19 Vaccine in Previously Vaccinated Adults · Phase 2 · recruiting
NCT07222384 — A Study to Learn About BNT162b2 (LP.8.1)-Adapted Vaccine Against SARS-CoV-2 in Children 5 Through 11 Years of Age That A · Phase 3 · active not recruiting

Other Hospital San Carlos, Madrid trials

Trials by the same sponsor.

NCT06310941 — Mechanical Insufflation-exsufflation and Hypertonic Saline in Nosocomial Bacterial Respiratory Tract Infection · NA · not yet recruiting
NCT07002658 — Clinical Impact of Surgical Wound Morbidity According to the Type of Saphenous Vein Harvesting Technique (Endoscopic vs. · NA · not yet recruiting
NCT06113939 — Prevention of Infection of the Respiratory Tract Through Application of Non-Invasive Methods of Secretion Suctioning · NA · not yet recruiting
NCT06156059 — Oral Bedtime Melatonin in Critically Ill Patients · Phase 4 · unknown
NCT07390175 — Ablation of Human Cardiac Fibrillation Based on Models of Hierarchical Organization of Tissue Excitation · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04525443 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Hospital San Carlos, Madrid
Last refreshed: 26 February 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04525443.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing