Last reviewed · How we verify
NCT04523948: THRRP
Comparative Tobacco Interventions for Individuals With Severe and Persisting Behavioral Health Disorders
trial testing Behavioral and pharmacological support to reduce combustible tobacco use. in Tobacco Use in 100 participants. Status unknown.
31 October 2022
Quick facts
| Lead sponsor | Rose Research Center, LLC |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 100 |
| Start date | 30 January 2020 |
| Primary completion | 31 October 2022 |
| Estimated completion | 31 July 2023 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Behavioral and pharmacological support to reduce combustible tobacco use.
Conditions studied
- Tobacco Use — all drugs for Tobacco Use →
Sponsor
Rose Research Center, LLC — full company profile →
Who can join
21 and older, any sex, with Tobacco Use. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of this pilot intervention is to examine the acceptability of a harm reduction intervention approach to tobacco use for individuals with serious behavioral health disorders and its association with a decrease in smoking. The intervention uses a "dynamic" approach to patient choice, allowing participants the option to explore different strategies for harm reduction, while providing support from counselors in the process. Therefore, the investigators have chosen an observational study design in order to document and explore the acceptability and outcomes of the intervention.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Results of an observational intervention trial: A promising harm reduction approach for persons with mental health and substance use disorders
McGirr K, Pratt S, Ferron J. · · 2024 · DOI 10.21203/rs.3.rs-4946979/v1
Verify or expand the search:
- PubMed search for NCT04523948
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Tobacco Use
Currently open trials in the same condition.
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- NCT07148232 — Extended Intervention for Tobacco Use (EXIT) for People Experiencing Homelessness · Phase 4 · recruiting
- NCT06983678 — Neural Correlates and Behavioral Impact of Withdrawal-induced Hyperalgesia Among People Who Smoke With and Without Chron · NA · recruiting
- NCT06922617 — STEPS: Substance Use Trial of E-cigarettes or Pharmacotherapy for Smoking · NA · recruiting
Other Rose Research Center, LLC trials
Trials by the same sponsor.
- NCT06554873 — Adaptive Use of Nicotine Substitution to Maintain Smoking Reduction/Abstinence in Nicotine Responders · Phase 3 · completed
- NCT06088862 — Evaluate Harm Reduction Products as a Second Line Intervention for Adult Smokers Who Do Not Quit With NRT · Phase 3 · terminated
- NCT05994703 — Assisting Smokers to Switch to an e-Cigarette by Accelerating Learning of Adaptive Habits Using D-cycloserine · Phase 2 · completed
- NCT05855343 — Exploratory Study of Switching From Combustible Cigarettes to the BIDI E-cigarette · NA · completed
- NCT05205811 — The Effects of Combination Zonisamide and Bupropion on Switching to an Electronic Cigarette · Phase 3 · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04523948 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Rose Research Center, LLC
- Last refreshed: 28 September 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04523948.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing