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NCT04522427
Study of Presbyopia-correcting Intraocular Lenses in Eyes With Previous Corneal Refractive Surgery
NA trial testing Use Multifocal and Extended Depth-of-Focus Intraocular Lenses(IOLs) in Cataract in 114 participants. Status unknown.
31 August 2021
Quick facts
| Lead sponsor | Eye & ENT Hospital of Fudan University |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 114 |
| Start date | 1 September 2020 |
| Primary completion | 31 August 2021 |
| Estimated completion | 31 August 2022 |
| Sites | 1 location across China |
Drugs / interventions tested
- Use Multifocal and Extended Depth-of-Focus Intraocular Lenses(IOLs)
- Use Monofocal intraocular lenses(IOLs)
Conditions studied
- Cataract — all drugs for Cataract →
- Presbyopia — all drugs for Presbyopia →
Sponsor
Eye & ENT Hospital of Fudan University
Who can join
18 and older, any sex, with Cataract or Presbyopia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This is a single-center, randomized, open, positive product, parallel controlled trial to evaluate the clinical outcomes of presbyopia-correcting intraocular lenses(IOLs) in eyes with previous corneal refractive surgery. Specific Aim 1 (Primary): To compare the surgical successful rate of Multifocal and Extended Depth-of-Focus IOLs with Monofocal IOLs for the treatment in eyes with previous corneal refractive surgery. Specific Aim 2 (Secondary): To study the suboptimal surgical outcomes between Multifocal and Extended Depth-of-Focus IOLs with Monofocal IOLs for the treatment in eyes with previous corneal refractive surgery.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Trifocal versus extended depth of focus (EDOF) intraocular lenses after cataract extraction.
Tavassoli S, Ziaei H, Yadegarfar ME, Gokul A, et al · · 2024 · cited 21× · PMID 38984608 · DOI 10.1002/14651858.cd014891.pub2
Verify or expand the search:
- PubMed search for NCT04522427
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Eye & ENT Hospital of Fudan University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04522427 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Eye & ENT Hospital of Fudan University
- Last refreshed: 21 August 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04522427.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing