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NCT04518358

Expert Guiding Technology to Help Individuals With Developmental Challenges Build Life and Vocational Skills

Completed NA Results posted Last updated 26 April 2024
What this trial tests

NA trial testing Use of Expert Guiding Technology (GAINS) to Improve Live and Vocational Skills for Individuals with Developmental Challenges in Autism Spectrum Disorder in 16 participants. Completed in 31 August 2022.

Timeline
1 September 2019
Primary endpoint
31 August 2022
31 August 2022

Quick facts

Lead sponsorJohn T. Nosek
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationna
Designsingle group
Maskingnone
Primary purposetreatment
Enrollment16
Start date1 September 2019
Primary completion31 August 2022
Estimated completion31 August 2022
Sites1 location across United States

Drugs / interventions tested

Conditions studied

Sponsor

John T. Nosek

Who can join

Eligibility, any sex, with Autism Spectrum Disorder or Intellectual Disability. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Fidelity of Treatment Implementation SCED 1 Dyad 1 Instructor Primary · Single Case Research Design (SCRD): Multiple Baselines Repeated Measures Design. Repeated measures in baselines and repeated measures in the intervention will be taken after each intervention of the technology for approximately 3 weeks.

One dependent measure is the fidelity of the teaching protocol implemented by DSPs. Each teaching protocol is comprised of a series of specific steps. Fidelity of the teaching protocol will be evaluated through collection of "yes" responses for accurately following the protocol and "no" responses for not accurately following the protocol for each step of the chain. The percentage of accurate implementation of the protocol will be calculated by dividing the steps marked with "yes" by the total number of the steps (sum of steps with "yes" and "no") and multiplied by 100. Data will be collected t

Session 1 - Baseline
GroupValue95% CI
SCED 1 Instructor Dyad 133
Session 2 - Baseline
GroupValue95% CI
SCED 1 Instructor Dyad 111
Session 3 - Baseline
GroupValue95% CI
SCED 1 Instructor Dyad 155
Session 4 - Baseline
GroupValue95% CI
SCED 1 Instructor Dyad 155
Session 5 - Baseline
GroupValue95% CI
SCED 1 Instructor Dyad 177
Session 6 - Baseline
GroupValue95% CI
SCED 1 Instructor Dyad 166
Session 7 - Intervention
GroupValue95% CI
SCED 1 Instructor Dyad 175
Session 8 - Intervention
GroupValue95% CI
SCED 1 Instructor Dyad 1100
Fidelity of Treatment Implementation SCED 1 Dyad 2 Instructor Primary · Single Case Research Design (SCRD): Multiple Baselines Repeated Measures Design. Repeated measures in baselines and repeated measures in the intervention will be taken after each intervention of the technology for approximately 3 weeks.

One dependent measure is the fidelity of the teaching protocol implemented by DSPs. Each teaching protocol is comprised of a series of specific steps. Fidelity of the teaching protocol will be evaluated through collection of "yes" responses for accurately following the protocol and "no" responses for not accurately following the protocol for each step of the chain. The percentage of accurate implementation of the protocol will be calculated by dividing the steps marked with "yes" by the total number of the steps (sum of steps with "yes" and "no") and multiplied by 100. Data will be collected t

Session 1 - Baseline
GroupValue95% CI
SCED 1 Instructor Dyad 233
Session 2 - Baseline
GroupValue95% CI
SCED 1 Instructor Dyad 255
Session 3 - Baseline
GroupValue95% CI
SCED 1 Instructor Dyad 2100
Session 4 - Intervention
GroupValue95% CI
SCED 1 Instructor Dyad 220
Session 5 - Intervention
GroupValue95% CI
SCED 1 Instructor Dyad 286
Session 6 - Intervention
GroupValue95% CI
SCED 1 Instructor Dyad 2100
Session 7 - Intervention
GroupValue95% CI
SCED 1 Instructor Dyad 2100
Session 8 - Intervention
GroupValue95% CI
SCED 1 Instructor Dyad 2100
Fidelity of Treatment Implementation SCED 1 Dyad 3 Instructor Primary · Single Case Research Design (SCRD): Multiple Baselines Repeated Measures Design. Repeated measures in baselines and repeated measures in the intervention will be taken after each intervention of the technology for approximately 3 weeks.

One dependent measure is the fidelity of the teaching protocol implemented by DSPs. Each teaching protocol is comprised of a series of specific steps. Fidelity of the teaching protocol will be evaluated through collection of "yes" responses for accurately following the protocol and "no" responses for not accurately following the protocol for each step of the chain. The percentage of accurate implementation of the protocol will be calculated by dividing the steps marked with "yes" by the total number of the steps (sum of steps with "yes" and "no") and multiplied by 100. Data will be collected t

Session 1 - Baseline
GroupValue95% CI
SCED 1 Instructor Dyad 3100
Session 2 - Baseline
GroupValue95% CI
SCED 1 Instructor Dyad 355
Session 3 - Baseline
GroupValue95% CI
SCED 1 Instructor Dyad 344
Session 4 - Baseline
GroupValue95% CI
SCED 1 Instructor Dyad 366
Session 5 - Baseline
GroupValue95% CI
SCED 1 Instructor Dyad 388
Session 6 - Baseline
GroupValue95% CI
SCED 1 Instructor Dyad 3100
Session 7 - Baseline
GroupValue95% CI
SCED 1 Instructor Dyad 377
Session 8 - Baseline
GroupValue95% CI
SCED 1 Instructor Dyad 377
Fidelity of Treatment Implementation SCED 1 Dyad 4 Instructor Primary · Single Case Research Design (SCRD): Multiple Baselines Repeated Measures Design. Repeated measures in baselines and repeated measures in the intervention will be taken after each intervention of the technology for approximately 3 weeks.

One dependent measure is the fidelity of the teaching protocol implemented by DSPs. Each teaching protocol is comprised of a series of specific steps. Fidelity of the teaching protocol will be evaluated through collection of "yes" responses for accurately following the protocol and "no" responses for not accurately following the protocol for each step of the chain. The percentage of accurate implementation of the protocol will be calculated by dividing the steps marked with "yes" by the total number of the steps (sum of steps with "yes" and "no") and multiplied by 100. Data will be collected t

Session 1 - Baseline
GroupValue95% CI
SCED 1 Instructor Dyad 433
Session 2 - Baseline
GroupValue95% CI
SCED 1 Instructor Dyad 455
Session 3 - Baseline
GroupValue95% CI
SCED 1 Instructor Dyad 433
Session 4 - Baseline
GroupValue95% CI
SCED 1 Instructor Dyad 433
Session 5 - Baseline
GroupValue95% CI
SCED 1 Instructor Dyad 455
Session 6 - Baseline
GroupValue95% CI
SCED 1 Instructor Dyad 488
Session 7 - Baseline
GroupValue95% CI
SCED 1 Instructor Dyad 477
Session 8 - Baseline
GroupValue95% CI
SCED 1 Instructor Dyad 488
Fidelity of Treatment Implementation SCED 2 Dyad 1 Instructor Primary · Single Case Research Design (SCRD): Multiple Baselines Repeated Measures Design. Repeated measures in baselines and repeated measures in the intervention will be taken after each intervention of the technology for approximately 3 weeks.

One dependent measure is the fidelity of the teaching protocol implemented by DSPs. Each teaching protocol is comprised of a series of specific steps. Fidelity of the teaching protocol will be evaluated through collection of "yes" responses for accurately following the protocol and "no" responses for not accurately following the protocol for each step of the chain. The percentage of accurate implementation of the protocol will be calculated by dividing the steps marked with "yes" by the total number of the steps (sum of steps with "yes" and "no") and multiplied by 100. Data will be collected t

Session 1 - Baseline
GroupValue95% CI
SCED 2 Instructor Dyad 10
Session 2 - Baseline
GroupValue95% CI
SCED 2 Instructor Dyad 15.56
Session 3 - Baseline
GroupValue95% CI
SCED 2 Instructor Dyad 10
Session 4 - Baseline
GroupValue95% CI
SCED 2 Instructor Dyad 10
Session 5 - Intervention
GroupValue95% CI
SCED 2 Instructor Dyad 10
Session 6 - Intervention
GroupValue95% CI
SCED 2 Instructor Dyad 188.89
Session 7 - Intervention
GroupValue95% CI
SCED 2 Instructor Dyad 177.78
Session 8 - Intervention
GroupValue95% CI
SCED 2 Instructor Dyad 172.22
Fidelity of Treatment Implementation SCED 2 Dyad 2 Instructor Primary · Single Case Research Design (SCRD): Multiple Baselines Repeated Measures Design. Repeated measures in baselines and repeated measures in the intervention will be taken after each intervention of the technology for approximately 3 weeks.

One dependent measure is the fidelity of the teaching protocol implemented by DSPs. Each teaching protocol is comprised of a series of specific steps. Fidelity of the teaching protocol will be evaluated through collection of "yes" responses for accurately following the protocol and "no" responses for not accurately following the protocol for each step of the chain. The percentage of accurate implementation of the protocol will be calculated by dividing the steps marked with "yes" by the total number of the steps (sum of steps with "yes" and "no") and multiplied by 100. Data will be collected t

Session 1 - Baseline
GroupValue95% CI
SCED 2 Instructor Dyad 20
Session 2 - Baseline
GroupValue95% CI
SCED 2 Instructor Dyad 20
Session 3 - Baseline
GroupValue95% CI
SCED 2 Instructor Dyad 20
Session 4 - Baseline
GroupValue95% CI
SCED 2 Instructor Dyad 20
Session 5 - Baseline
GroupValue95% CI
SCED 2 Instructor Dyad 20
Session 6 - Baseline
GroupValue95% CI
SCED 2 Instructor Dyad 20
Session 7 - Baseline
GroupValue95% CI
SCED 2 Instructor Dyad 20
Session 8 - Baseline
GroupValue95% CI
SCED 2 Instructor Dyad 20
Fidelity of Treatment Implementation SCED 2 Dyad 3 Instructor Primary · Single Case Research Design (SCRD): Multiple Baselines Repeated Measures Design. Repeated measures in baselines and repeated measures in the intervention will be taken after each intervention of the technology for approximately 3 weeks.

One dependent measure is the fidelity of the teaching protocol implemented by DSPs. Each teaching protocol is comprised of a series of specific steps. Fidelity of the teaching protocol will be evaluated through collection of "yes" responses for accurately following the protocol and "no" responses for not accurately following the protocol for each step of the chain. The percentage of accurate implementation of the protocol will be calculated by dividing the steps marked with "yes" by the total number of the steps (sum of steps with "yes" and "no") and multiplied by 100. Data will be collected t

Session 1 - Baseline
GroupValue95% CI
SCED 2 Instructor Dyad 30
Session 2 - Baseline
GroupValue95% CI
SCED 2 Instructor Dyad 30
Session 3 - Baseline
GroupValue95% CI
SCED 2 Instructor Dyad 30
Session 4 - Baseline
GroupValue95% CI
SCED 2 Instructor Dyad 30
Session 5 - Baseline
GroupValue95% CI
SCED 2 Instructor Dyad 30
Session 6 - Baseline
GroupValue95% CI
SCED 2 Instructor Dyad 311.11
Session 7 - Baseline
GroupValue95% CI
SCED 2 Instructor Dyad 311.11
Session 8 - Baseline
GroupValue95% CI
SCED 2 Instructor Dyad 30
Fidelity of Treatment Implementation SCED 2 Dyad 4 Instructor Primary · Single Case Research Design (SCRD): Multiple Baselines Repeated Measures Design. Repeated measures in baselines and repeated measures in the intervention will be taken after each intervention of the technology for approximately 3 weeks.

One dependent measure is the fidelity of the teaching protocol implemented by DSPs. Each teaching protocol is comprised of a series of specific steps. Fidelity of the teaching protocol will be evaluated through collection of "yes" responses for accurately following the protocol and "no" responses for not accurately following the protocol for each step of the chain. The percentage of accurate implementation of the protocol will be calculated by dividing the steps marked with "yes" by the total number of the steps (sum of steps with "yes" and "no") and multiplied by 100. Data will be collected t

Session 1 - Baseline
GroupValue95% CI
SCED 2 Instructor Dyad 40
Session 2 - Baseline
GroupValue95% CI
SCED 2 Instructor Dyad 40
Session 3 - Baseline
GroupValue95% CI
SCED 2 Instructor Dyad 40
Session 4 - Baseline
GroupValue95% CI
SCED 2 Instructor Dyad 40
Session 5 - Baseline
GroupValue95% CI
SCED 2 Instructor Dyad 40
Session 6 - Baseline
GroupValue95% CI
SCED 2 Instructor Dyad 40
Session 7 - Baseline
GroupValue95% CI
SCED 2 Instructor Dyad 422.22
Session 8 - Baseline
GroupValue95% CI
SCED 2 Instructor Dyad 40
Independent Completion of Steps SCED 1 Dyad 1 Adult With ASD Primary · Single Case Research Design (SCRD): Multiple Baselines Repeated Measures Design. Repeated measures in baselines and repeated measures in the intervention will be taken after each intervention of the technology for approximately 3 weeks.

Each target skill performed by adults with ASD/ID will be task analyzed. Tasks analysis involves breaking the skill down into smaller steps. The percentage of independent completion of steps will be calculated by dividing the number of independently completed steps by the total number of steps and multiplying by 100. Data will be captured through multiple trials to make visual analysis possible.

Session 1 - Baseline
GroupValue95% CI
SCED 1 Dyad 1 Adult With ASD22
Session 2 - Baseline
GroupValue95% CI
SCED 1 Dyad 1 Adult With ASD33
Session 3 - Baseline
GroupValue95% CI
SCED 1 Dyad 1 Adult With ASD55
Session 4 - Baseline
GroupValue95% CI
SCED 1 Dyad 1 Adult With ASD44
Session 5 - Baseline
GroupValue95% CI
SCED 1 Dyad 1 Adult With ASD77
Session 6 - Baseline
GroupValue95% CI
SCED 1 Dyad 1 Adult With ASD77
Session 7 - Intervention
GroupValue95% CI
SCED 1 Dyad 1 Adult With ASD33
Session 8 - Intervention
GroupValue95% CI
SCED 1 Dyad 1 Adult With ASD77
Independent Completion of Steps SCED 1 Dyad 2 Adult With ASD Primary · Single Case Research Design (SCRD): Multiple Baselines Repeated Measures Design. Repeated measures in baselines and repeated measures in the intervention will be taken after each intervention of the technology for approximately 3 weeks.

Each target skill performed by adults with ASD/ID will be task analyzed. Tasks analysis involves breaking the skill down into smaller steps. The percentage of independent completion of steps will be calculated by dividing the number of independently completed steps by the total number of steps and multiplying by 100. Data will be captured through multiple trials to make visual analysis possible.

Session 1 - Baseline
GroupValue95% CI
SCED 1 Dyad 2 Adult With ASD22
Session 2 - Baseline
GroupValue95% CI
SCED 1 Dyad 2 Adult With ASD44
Session 3 - Baseline
GroupValue95% CI
SCED 1 Dyad 2 Adult With ASD55
Session 4 - Intervention
GroupValue95% CI
SCED 1 Dyad 2 Adult With ASD80
Session 5 - Intervention
GroupValue95% CI
SCED 1 Dyad 2 Adult With ASD66
Session 6 - Intervention
GroupValue95% CI
SCED 1 Dyad 2 Adult With ASD66
Session 7 - Intervention
GroupValue95% CI
SCED 1 Dyad 2 Adult With ASD77
Session 8 - Intervention
GroupValue95% CI
SCED 1 Dyad 2 Adult With ASD66
Independent Completion of Steps SCED 1 Dyad 3 Adult With ASD Primary · Single Case Research Design (SCRD): Multiple Baselines Repeated Measures Design. Repeated measures in baselines and repeated measures in the intervention will be taken after each intervention of the technology for approximately 3 weeks.

Each target skill performed by adults with ASD/ID will be task analyzed. Tasks analysis involves breaking the skill down into smaller steps. The percentage of independent completion of steps will be calculated by dividing the number of independently completed steps by the total number of steps and multiplying by 100. Data will be captured through multiple trials to make visual analysis possible.

Session 1 - Baseline
GroupValue95% CI
SCED 1 Dyad 3 Adult With ASD66
Session 2 - Baseline
GroupValue95% CI
SCED 1 Dyad 3 Adult With ASD77
Session 3 - Baseline
GroupValue95% CI
SCED 1 Dyad 3 Adult With ASD33
Session 4 - Baseline
GroupValue95% CI
SCED 1 Dyad 3 Adult With ASD33
Session 5 - Baseline
GroupValue95% CI
SCED 1 Dyad 3 Adult With ASD66
Session 6 - Baseline
GroupValue95% CI
SCED 1 Dyad 3 Adult With ASD100
Session 7 - Baseline
GroupValue95% CI
SCED 1 Dyad 3 Adult With ASD88
Session 8 - Baseline
GroupValue95% CI
SCED 1 Dyad 3 Adult With ASD77
Independent Completion of Steps SCED 1 Dyad 4 Adult With ASD Primary · Single Case Research Design (SCRD): Multiple Baselines Repeated Measures Design. Repeated measures in baselines and repeated measures in the intervention will be taken after each intervention of the technology for approximately 3 weeks.

Each target skill performed by adults with ASD/ID will be task analyzed. Tasks analysis involves breaking the skill down into smaller steps. The percentage of independent completion of steps will be calculated by dividing the number of independently completed steps by the total number of steps and multiplying by 100. Data will be captured through multiple trials to make visual analysis possible.

Session 1 - Baseline
GroupValue95% CI
SCED 1 Dyad 4 Adult With ASD33
Session 2 - Baseline
GroupValue95% CI
SCED 1 Dyad 4 Adult With ASD55
Session 3 - Baseline
GroupValue95% CI
SCED 1 Dyad 4 Adult With ASD55
Session 4 - Baseline
GroupValue95% CI
SCED 1 Dyad 4 Adult With ASD44
Session 5 - Baseline
GroupValue95% CI
SCED 1 Dyad 4 Adult With ASD55
Session 6 - Baseline
GroupValue95% CI
SCED 1 Dyad 4 Adult With ASD77
Session 7 - Baseline
GroupValue95% CI
SCED 1 Dyad 4 Adult With ASD77
Session 8 - Baseline
GroupValue95% CI
SCED 1 Dyad 4 Adult With ASD55

Sponsor's own description

Clinical trials will evaluate the efficacy of expert guiding technology to support instructors to better help individuals with developmental challenges due to ASD and ID learn life and vocational skills. Single Case Research Designs (SCRD) will be used to evaluate expert guiding technology interventions to support Task Analysis. SCRDs are a viable alternative to large group studies such as randomized clinical trials. Single case studies involve repeated measures, and manipulation of an independent variable. SCRD studies allow for rigorous experimental evaluation of intervention effects and provide a strong basis for establishing causal inferences. Research design: A multiple baseline across tasks or participants will be used to evaluate the impact of the expert guiding technology on staff and consumers' performance. Dependent Variables. DV1: Staff performance: The percentage of teaching steps correctly implemented will be calculated and monitored. The teaching steps are predetermined including what types of prompts will be used for each step of the task analysis of the identified consumer's adaptive living skills, record data on consumer's performance, and the timing of delivery of reinforcers and prompts. DV2: Consumers' performance: The percentage of Independent completion of the steps of task analyses for identified daily living skills will be calculated and monitored. The completed step is considered "independent" when the consumer completed the step without prompts from the staff within five seconds of the initial instruction (discriminative stimulus) given or the completion of the previous step. DV3: Consumers' performance: the amount of time taken to independent completion. Independent Variable: Versions of expert guiding technology to support instructors in providing Task Analyses instruction while collecting data on consumer performance. GAINS: During the GAINS sessions, the staff will follow the pre-programmed teaching protocol in the expert guiding technology. The system will provide step-by-step verbal prompts to the staff throughout the sessions. This includes which prompt to use for each step, when to provide reinforcers, and which target task to work on. The system will also monitor the consumer's progress and notify the staff if the target task is mastered or not.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

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Data sources for this page

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing