Who is sponsoring NCT04516005?

NCT04516005 is sponsored by Khon Kaen University.

What drugs are being tested in NCT04516005?

Interventions in NCT04516005: foot reflexology.

What condition does NCT04516005 study?

NCT04516005 studies Reflexology, Hypertension, Acupressure, Traditional Medicine.

Is NCT04516005 still recruiting?

NCT04516005 is currently completed. Last updated 17 August 2020.

Last reviewed 2020-08-17 · How we verify

NCT04516005

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effect of Foot Reflexology on Blood Pressure and Pulse Rate: A Randomized Clinical Trial

Completed NA Last updated 17 August 2020

What this trial tests

NA trial testing foot reflexology in Reflexology, Hypertension, Acupressure, Traditional Medicine in 94 participants. Completed in 31 October 2016.

Timeline

1 November 2015

Primary endpoint
31 May 2016

31 October 2016

Quick facts

Lead sponsor	Khon Kaen University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	94
Start date	1 November 2015
Primary completion	31 May 2016
Estimated completion	31 October 2016

Drugs / interventions tested

foot reflexology

Conditions studied

Reflexology, Hypertension, Acupressure, Traditional Medicine — all drugs for Reflexology, Hypertension, Acupressure, Traditional Medicine →

Sponsor

Khon Kaen University

Who can join

Adults 18 to 80, any sex, with Reflexology, Hypertension, Acupressure, Traditional Medicine. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Hypertension (HT) has been known for its prominent risk of cardiovascular events. Although there are various pharmacological choices, many patients fail to adhere with them. Therefore, adjunctive non-pharmacological treatment is a promising approach. Foot Reflexology is one of a complementary therapies that has been proved for its ability to decrease blood pressure (BP), however, there is limited data in patients with stage-2 HT. We aimed to examine the effectiveness of foot reflexology as adjunctive therapy for BP lowering. This was a single-center randomized clinical trial. Hypertensive patients who were regularly followed up at the hypertension clinic were enrolled and randomized into the intervention group (n=47) and control group (n=47). Foot reflexology was performed in the intervention group during a clinical visit. Office BP and pulse rate (PR) were measured before and immediately at 15 minutes (min) and 30 min after the procedure in the intervention group and after resting in the control group.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

The effects of foot reflexology on blood pressure and heart rate: A randomized clinical trial in stage-2 hypertensive patients.
Kotruchin P, Imoun S, Mitsungnern T, Aountrai P, et al · · 2021 · cited 5× · PMID 33190420 · DOI 10.1111/jch.14103

Verify or expand the search:

Other trials of foot reflexology

Trials testing the same drug.

NCT06875349 — Foot Reflexology and Abdominal Massage · NA · completed
NCT05631522 — Effect of Foot Reflexology on Pain Associated With Mediastinal Chest Drain Removal · NA · unknown
NCT04924439 — Effects of Reflexology on Postpartum Pain, Fatigue, Sleep Quality and Lactation · NA · completed
NCT03882086 — Foot Reflexology on Postpartum Sleep Qualıty · NA · completed
NCT04348201 — Foot Reflexology on Premenstrual Syndrome · NA · completed

Other Khon Kaen University trials

Trials by the same sponsor.

NCT07494396 — An AI-Based Erythema Measurement System for Psoriasis Lesions · not yet recruiting
NCT07054775 — Comparison of Pruritus Incidence After Intrathecal Morphine 0.1 vs 0.2 mg in Cesarean Section · Phase 4 · recruiting
NCT06994520 — Efficacy of Topical Cannabidiol for Eczema · Phase 2 · active not recruiting
NCT06958029 — Postoperative Atrial Fibrillation in Cardiac Surgery · recruiting
NCT06289257 — Analysis of Vitamin D and VDR Expression in Endometriosis: A Case-Control Study · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04516005 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Khon Kaen University
Last refreshed: 17 August 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04516005.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing