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NCT04513600
ATTR-Cardiomyopathy Stabilization Following Tafamidis Therapy
trial testing Cardiac MRI in Transthyretin Amyloidosis in 131 participants. Status unknown.
1 August 2022
Quick facts
| Lead sponsor | The Christ Hospital |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 131 |
| Start date | 1 August 2020 |
| Primary completion | 1 August 2022 |
| Estimated completion | 1 August 2023 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Cardiac MRI
Conditions studied
- Transthyretin Amyloidosis — all drugs for Transthyretin Amyloidosis →
Sponsor
The Christ Hospital
Who can join
Adults 18 to 90, any sex, with Transthyretin Amyloidosis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The study will investigate the stabilization effects of Tafamidis utilizing cardiac imaging cardiac magnetic resonance imaging (CMR). The investigators propose to pursue the following specific aims: 1. Utilize cardiac magnetic resonance to assess stabilization of ATTR after Tafamidis therapy based on extracellular volume mapping. 2. Investigate left ventricular myocardial mass, native T1, T2, and extracellular volume mapping after 12 month follow-up. 3. Utilize cardiac magnetic resonance feature tracking at baseline and at 12 month follow-up.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04513600
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other recruiting trials for Transthyretin Amyloidosis
Currently open trials in the same condition.
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Other The Christ Hospital trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04513600 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by The Christ Hospital
- Last refreshed: 27 January 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04513600.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing