Last reviewed · How we verify

NCT04511481

Deep Learning Magnetic Resonance Imaging Radiomic Predict Platinum-sensitive in Patients With Epithelial Ovarian Cancer

Status unknown Last updated 13 August 2020
What this trial tests

trial testing Radiomic Algorithm in Predictive Cancer Model in 93 participants. Status unknown.

Timeline
15 April 2020
Primary endpoint
3 August 2020
1 January 2021

Quick facts

Lead sponsorSun Yat-Sen Memorial Hospital of Sun Yat-Sen University
StatusStatus unknown
Study typeOBSERVATIONAL
Enrollment93
Start date15 April 2020
Primary completion3 August 2020
Estimated completion1 January 2021
Sites1 location across China

Drugs / interventions tested

Conditions studied

Sponsor

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Who can join

Adults 22 to 99, female only, with Predictive Cancer Model. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Platinum-sensitive is an important basis for the treatment of recurrent epithelial ovarian cancer (EOC) without effective methods to predict.We aimed to develop and validate the EOC deep learning system to predict the platinum-sensitive of EOC patients through analysis of enhanced magnetic resonance imaging (MRI) images before initial treatment.Ninety-three EOC patients received platinum-based chemotherapy (\>= 4 cycles) and debulking surgery from Sun Yat-sen Memorial Hospitalin China from January 2011 to January 2020 were enrolled. This deep-learning EOC signature achieved a high predictive power for platinum-sensitive, and the signature based on MRI whole volume is better than that on primary tumor area only.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Deep learning magnetic resonance imaging predicts platinum sensitivity in patients with epithelial ovarian cancer.
    Lei R, Yu Y, Li Q, Yao Q, et al · · 2022 · cited 9× · PMID 36505880 · DOI 10.3389/fonc.2022.895177

Verify or expand the search:

Other trials of Radiomic Algorithm

Trials testing the same drug.

Other recruiting trials for Predictive Cancer Model

Currently open trials in the same condition.

Other Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04511481.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing