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NCT04509739

Effect of Music Intervention on Infants' Brainstem Encoding of Speech

Terminated NA Results posted Last updated 17 May 2022
What this trial tests

NA trial testing Music intervention in Infant Development in 17 participants. Terminated before completion.

Timeline
16 October 2019
Primary endpoint
15 March 2020
15 March 2020

Quick facts

Lead sponsorUniversity of Washington
PhaseNA
StatusTerminated
Study typeINTERVENTIONAL
Allocationna
Designsingle group
Maskingnone
Primary purposebasic science
Enrollment17
Start date16 October 2019
Primary completion15 March 2020
Estimated completion15 March 2020
Sites1 location across United States

Drugs / interventions tested

Conditions studied

Sponsor

University of Washington

Who can join

Adults 6 Months to 12 Months, any sex, with Infant Development. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

FFR-stimulus-f0 Correlation Primary · The outcome measure was taken within 2 weeks following the completion of music intervention (i.e., the last intervention session)

The FFR-stimulus-f0 correlation is an index of how well the auditory brainstem encode speech signals. It is calculated as the correlation coefficient between the fundamental frequency (f0) extracted from the stimulus and the f0 extracted from the FFR. The coefficient ranges between -1 to 1, with 1 indexing perfect positive correlation, -1 indexing perfect negative correlation and 0 indexing no correlation. Here, correlation in either direction is considered better than non-correlation.

GroupValue95% CI
Music Intervention0.048± 0.331

Sponsor's own description

Infants' frequency-following response (FFR) to a nonnative lexical tone, reflecting early sensory encoding of speech in the auditory system will be evaluated pre- and post- music intervention at 7 mo and 11 mo of age. The lab-controlled music intervention starts at 9 mo of age and consists of 12 sessions of social and multimodel musical activities with the aim to synchronize infants' movements with musical beats.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Language experience during the sensitive period narrows infants' sensory encoding of lexical tones-Music intervention reverses it.
    Zhao TC, Llanos F, Chandrasekaran B, Kuhl PK. · · 2022 · cited 5× · PMID 36016666 · DOI 10.3389/fnhum.2022.941853

Verify or expand the search:

Other trials of Music intervention

Trials testing the same drug.

Other recruiting trials for Infant Development

Currently open trials in the same condition.

Other University of Washington trials

Trials by the same sponsor.

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Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04509739.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing