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Orphenadrine Versus Baclofen in Treatment of Muscle Cramps in Cirrhotic Patients
Muscle cramps are commonly affects patients with cirrhosis. It adversely influences the quality of life of cirrhotic patients. Treatment of muscle cramps still challenging owing to the diversity of the responsible pathophysiological mechanisms.The effectiveness of baclofen and orphenadrine in controlling muscle cramps in cirrhotic patients has been presented in recent randomised controlled clinical trials;however, the comparative efficacy and safety between these two therapeutic options has not been previously investigated.
Details
| Lead sponsor | Mansoura University |
|---|---|
| Phase | NA |
| Status | TERMINATED |
| Enrolment | 5 |
| Start date | Thu Aug 20 2020 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Mon Sep 20 2021 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Cirrhosis
Interventions
- Orphenadrine
- Baclofen
Countries
Egypt