NCT04507516 (FBHH) is a clinical trial of Water-only Fasting in Insulin Resistance, sponsored by TrueNorth Health Foundation.

Who is sponsoring NCT04507516?

NCT04507516 is sponsored by TrueNorth Health Foundation.

What drugs are being tested in NCT04507516?

Interventions in NCT04507516: Water-only Fasting.

What condition does NCT04507516 study?

NCT04507516 studies Insulin Resistance.

Is NCT04507516 still recruiting?

NCT04507516 is currently completed. Last updated 11 August 2020.

Last reviewed 2020-08-11 · How we verify

NCT04507516: FBHH

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Fasting for Brain and Heart Health (FBHH)

Completed Last updated 11 August 2020

What this trial tests

trial testing Water-only Fasting in Insulin Resistance in 48 participants. Completed in 10 February 2020.

Timeline

2 April 2019

Primary endpoint
10 February 2020

10 February 2020

Quick facts

Lead sponsor	TrueNorth Health Foundation
Status	Completed
Study type	OBSERVATIONAL
Enrollment	48
Start date	2 April 2019
Primary completion	10 February 2020
Estimated completion	10 February 2020
Sites	1 location across United States

Drugs / interventions tested

Water-only Fasting

Conditions studied

Insulin Resistance — all drugs for Insulin Resistance →

Sponsor

TrueNorth Health Foundation

Who can join

Adults 40 to 70, any sex, with Insulin Resistance. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This pilot study is designed to investigate the effect of water-only fasting and refeeding on the homeostatic model of insulin resistance (HOMA-IR), a measure of insulin resistance.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

The Effects of Prolonged Water-Only Fasting and Refeeding on Markers of Cardiometabolic Risk.
Scharf E, Zeiler E, Ncube M, Kolbe P, et al · · 2022 · cited 8× · PMID 35334843 · DOI 10.3390/nu14061183

Verify or expand the search:

Other trials of Water-only Fasting

Trials testing the same drug.

NCT04515095 — Water-only Fasting in the Treatment of Hypertension Patients · NA · completed

Other recruiting trials for Insulin Resistance

Currently open trials in the same condition.

NCT07403604 — Effect of Insulin Lowering on Lipogenesis · Phase 1 · recruiting
NCT07226128 — The Effects of Cognitive Behavioral Therapy on Insulin Resistance in People With HIV · NA · recruiting
NCT07505745 — MOTS-c for Improving Insulin Sensitivity in Adults With Prediabetes and Overweight/Obesity · Phase 2 · recruiting
NCT07220694 — Effects of Sabroxy® Supplementation on Insulin Resistance and Cognitive Function in Adults With Mild Cognitive Impairmen · NA · recruiting
NCT06768827 — New Mechanisms of Obesity · NA · recruiting

Other TrueNorth Health Foundation trials

Trials by the same sponsor.

NCT04515095 — Water-only Fasting in the Treatment of Hypertension Patients · NA · completed
NCT04514146 — The Effects of Water-only Fasting and Refeeding on Body Composition · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04507516 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by TrueNorth Health Foundation
Last refreshed: 11 August 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04507516.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing