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NCT04506801
The Effect of Probiotics on Functional Constipation in the Elderly
NA trial testing Probalans senior in Functional Constipation in 60 participants. Completed in 25 May 2019.
25 March 2019
Quick facts
| Lead sponsor | Katarina Fehir Šola |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | health services research |
| Enrollment | 60 |
| Start date | 25 September 2018 |
| Primary completion | 25 March 2019 |
| Estimated completion | 25 May 2019 |
| Sites | 1 location across Croatia |
Drugs / interventions tested
- Probalans senior
- Placebo
Conditions studied
- Functional Constipation — all drugs for Functional Constipation →
Sponsor
Katarina Fehir Šola
Who can join
60 and older, any sex, with Functional Constipation. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The main scope of the proposed research in the framework is to investigate the effect of probiotic bacteria Lactobacillus acidophilus LA3, Bifidobacterium animalis ssp. lactis BLC1 i Lactobacillus casei BGP93 on functional constipation and on the quality of life of the elderly in a nursing home. The experimental part will consists of double-blind, placebo-controlled clinical trial over 12 weeks.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
The effect of multistrain probiotics on functional constipation in the elderly: a randomized controlled trial.
Šola KF, Vladimir-Knežević S, Hrabač P, Mucalo I, et al · · 2022 · cited 20× · PMID 35927504 · DOI 10.1038/s41430-022-01189-0 -
Recent advances in therapeutic probiotics: insights from human trials.
Cho M-Y, Eom J-H, Choi E-M, Yang S-J, et al · · 2025 · cited 17× · PMID 40261032 · DOI 10.1128/cmr.00240-24
Verify or expand the search:
- PubMed search for NCT04506801
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Functional Constipation
Currently open trials in the same condition.
- NCT07148583 — BioAmicus Complete for Functional Gastrointestinal Symptoms in Infants Aged 0 to 24 Months · NA · recruiting
- NCT07091084 — A Study of Herbal Supplements in Cancer Survivors With Constipation · NA · recruiting
- NCT06534996 — A Single Arm Pilot Study of the Chinese Herbal Medicine Formula (SCD-2101) for the Functional Constipation in the Elderl · NA · recruiting
- NCT04918329 — Functional Digestive Disorders Observatory · recruiting
- NCT04547816 — Efficacy of Conservative Treatment of Functional Defecatory Disorders in Females With Pelvic Organ Prolapse · Phase 3 · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04506801 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Katarina Fehir Šola
- Last refreshed: 10 August 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04506801.
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