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Regulation of Mucosal Healing in Inflammatory Bowel Disease
The objective of the current study is to compare non-healing colonic ulcers in patients with inflammatory bowel disease (IBD) with iatrogenic colonic ulcers (biopsy sites) in healthy control patients and patients with rheumatoid or psoriatic arthritis. Patients will be biopsied at baseline and again at a follow-up visit in a "biopsy of the biopsy" approach. These biopsies will be used to reveal patterns about gene expression and mitochondrial function during ulcer healing.
Details
| Lead sponsor | Terrence A Barrett |
|---|---|
| Phase | NA |
| Status | RECRUITING |
| Enrolment | 60 |
| Start date | Fri Apr 30 2021 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Mon Jun 01 2026 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Inflammatory Bowel Diseases
Interventions
- Serial Biopsy
Countries
United States