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NCT04502355

Voriconazole-Induced QT Interval Prolongation: A Prospective Study

Status unknown Last updated 6 August 2020
What this trial tests

trial in Voriconazole Induced QT Interval Prolongation in 60 participants. Status unknown.

Timeline
31 October 2016
Primary endpoint
31 December 2020
31 December 2020

Quick facts

Lead sponsorRabin Medical Center
StatusStatus unknown
Study typeOBSERVATIONAL
Enrollment60
Start date31 October 2016
Primary completion31 December 2020
Estimated completion31 December 2020
Sites1 location across Israel

Conditions studied

Sponsor

Rabin Medical Center

Who can join

Under 20, any sex, with Voriconazole Induced QT Interval Prolongation. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The antifungal voriconazole is effective for the treatment of invasive fungal infections in immunocompromised patients. A serious adverse reaction is QT interval prolongation, which may precede life-threatening arrhythmias, such as torsades de pointes. Although ventricular arrhythmias are mentioned as a possible adverse effect of voriconazole, thus far, the incidence and clear recommendations for QT follow-up have not been published. This prospective observational study aimed at describing the incidence of voriconazole induced- QT interval prolongation in the pediatric population and determine the risk factors for this phenomenon.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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Other Rabin Medical Center trials

Trials by the same sponsor.

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Data sources for this page

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