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Prophylactic Antibiotics for Urinary Tract Infections After Robot-Assisted Radical Cystectomy
This trial investigates whether a one-month course of preventative (prophylactic) antibiotics helps to reduce urinary tract infections after robot-assisted surgery to remove all of the bladder as well as nearby tissues and organs (radical cystectomy). Urinary tract infections are a common occurrence after robot-assisted radical cystectomy. Antibiotics such as trimethoprim-sulfamethoxazole or nitrofurantoin may prevent or control infections in patients with urinary tract infection and may help improve their response to radical cystectomy. Information gained from this study may help researchers to predict patient complications and identify better ways to manage these complications.
Details
| Lead sponsor | Roswell Park Cancer Institute |
|---|---|
| Phase | PHASE4 |
| Status | COMPLETED |
| Enrolment | 89 |
| Start date | Wed Sep 02 2020 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Thu Mar 13 2025 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Bladder Carcinoma
- Refractory Bladder Carcinoma
- Urinary Tract Infection
Interventions
- Clindamycin
- Diary
- Ertapenem
- Levofloxacin
- Nitrofurantoin
- Trimethoprim-Sulfamethoxazole
Countries
United States