NCT04499820 (OMEDIA) is a NA clinical trial of Nutrof in Diabetic Retinopathy, sponsored by Centre Hospitalier Intercommunal Creteil.

Who is sponsoring NCT04499820?

NCT04499820 is sponsored by Centre Hospitalier Intercommunal Creteil.

What drugs are being tested in NCT04499820?

Interventions in NCT04499820: Nutrof, Meralut.

What condition does NCT04499820 study?

NCT04499820 studies Diabetic Retinopathy.

Is NCT04499820 still recruiting?

NCT04499820 is currently completed. Last updated 4 December 2025.

Last reviewed 2025-12-04 · How we verify

NCT04499820: OMEDIA

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effect of OMEGA3 Supplementation in Diabetic Retinopathy

Completed NA Last updated 4 December 2025

What this trial tests

NA trial testing Nutrof in Diabetic Retinopathy in 60 participants. Completed in 17 April 2025.

Timeline

26 June 2020

Primary endpoint
10 October 2024

17 April 2025

Quick facts

Lead sponsor	Centre Hospitalier Intercommunal Creteil
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	supportive care
Enrollment	60
Start date	26 June 2020
Primary completion	10 October 2024
Estimated completion	17 April 2025
Sites	1 location across France

Drugs / interventions tested

Nutrof
Meralut

Conditions studied

Diabetic Retinopathy — all drugs for Diabetic Retinopathy →

Sponsor

Centre Hospitalier Intercommunal Creteil

Who can join

18 and older, any sex, with Diabetic Retinopathy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The main objective of this study is to evaluate the efficacy at 6 months of omega 3 supplementation on macular capillary density measured in optical coherence tomography angiography in patients with minimal or moderate non proliferative diabetic retinopathy.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Microglia in retinal angiogenesis and diabetic retinopathy.
Hu A, Schmidt MHH, Heinig N. · · 2024 · cited 54× · PMID 38564108 · DOI 10.1007/s10456-024-09911-1
Inherited Retinal Dystrophies: Role of Oxidative Stress and Inflammation in Their Physiopathology and Therapeutic Implications.
Pinilla I, Maneu V, Campello L, Fernández-Sánchez L, et al · · 2022 · cited 30× · PMID 35739983 · DOI 10.3390/antiox11061086

Verify or expand the search:

Other recruiting trials for Diabetic Retinopathy

Currently open trials in the same condition.

NCT07255326 — Effect of Omega-3 Fatty Acids on Eye Blood Vessels in Type 1 Diabetes · NA · recruiting
NCT06782997 — Performance of the Electroretinogram, Performed and Interpreted by an Advanced Practice Nurse, in the Screening for Diab · recruiting
NCT07002372 — Effect of Video Viewing on Intravitreal Injection Experience · NA · recruiting
NCT06713720 — Remote Ischemic Conditioning for Non-Proliferative Diabetic Retinopathy · NA · recruiting
NCT06892353 — AI-Powered DIY Screening System for Diabetic Retinopathy · NA · recruiting

Other Centre Hospitalier Intercommunal Creteil trials

Trials by the same sponsor.

NCT07493785 — Dexmedetomidine for Invasive Ventilation In the NEOnate · Phase 2, PHASE3 · not yet recruiting
NCT07513051 — DIaphragmatic Swing According to Cpap Flow Output in NEOnates (DISCONEO) · NA · not yet recruiting
NCT07455942 — Towards an Understanding of Barriers and Delays in the Diagnosis of Anal Cancer · not yet recruiting
NCT07153367 — Using a Fixed Dosage of Follitropin Delta for Ovarian Stimulation for Intrauterine Insemination: Rekovelle for Intrauter · Phase 2 · recruiting
NCT06339450 — Real World Environmental Exposure Study With Healthy and Cystic Fibrosis Subjects · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04499820 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Centre Hospitalier Intercommunal Creteil
Last refreshed: 4 December 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04499820.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing