NCT04498975

Exploring Potential Associations Between Rurality and Hopelessness in IHD Patients

Completed Last updated 18 May 2021

What this trial tests

trial testing Rurality; Ethnicity; Exercise; Hopelessness in Cardiac Disease in 125 participants. Completed in 1 August 2020.

Timeline

1 June 2018

Primary endpoint
1 August 2020

1 August 2020

Quick facts

Lead sponsor	Dordt University
Status	Completed
Study type	OBSERVATIONAL
Enrollment	125
Start date	1 June 2018
Primary completion	1 August 2020
Estimated completion	1 August 2020
Sites	2 locations across United States

Drugs / interventions tested

• Rurality; Ethnicity; Exercise; Hopelessness

Conditions studied

• Cardiac Disease — all drugs for Cardiac Disease →
• Mental Health Issue — all drugs for Mental Health Issue →

Sponsor

Dordt University

Who can join

Eligibility, any sex, with Cardiac Disease or Mental Health Issue. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Hopelessness is associated with 3.4 times increased risk of mortality or nonfatal myocardial infarction in patients with ischemic heart disease (IHD), independent of depression. Hopelessness has been identified in 27-52% of patients with IHD and can persist for up to 12 months after hospital discharge. Hopelessness, a negative outlook and sense of helplessness toward the future, can be a temporary response to an event (state) or a habitual outlook (trait). Hopelessness is associated with decreased physical functioning and lower physical activity (PA) levels in individuals with IHD. Low levels of PA independently contribute to increased death and adverse events in patients with IHD. Rates of PA in IHD patients continue to be unacceptably low in both hospital-based cardiac rehabilitation and home settings. Compounding this issue is often the symptom of hopelessness. The links among hopelessness, PA and mortality and morbidity for patients with IHD remain largely unknown, especially in rural and minority IHD patients. The purpose of this study is to delineate differences in hopelessness between urban and rural patients with IHD, as well as between racial minority, including Hispanic and Native American, and White patients with IHD. Potential mediation of urbanicity and race/ethnicity by social connectedness, a key variable in rural settings, will also be examined. A 6-month longitudinal study will be conducted at Sanford Heart Hospital and Avera Health in Sioux Falls, South Dakota. Hopelessness will be measured using the State-Trait Hopelessness Scale. The results of this study have potential to transform nursing practice by providing a better understanding of hopelessness in IHD patients and informing future exercise rehabilitation studies and interventions in rural and minority populations.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Investigating Rurality as a Risk Factor for State and Trait Hopelessness in Hospitalized Patients With Ischemic Heart Disease.
   Bomgaars D, Jensen GA, White LL, Van De Griend KM, et al · · 2021 · PMID 34465185 · DOI 10.1161/jaha.121.020768