NCT04493398

Air-polishing or Conventional Treatment

Completed NA Last updated 30 July 2020

What this trial tests

NA trial testing Gracey curette. in Periodontitis in 20 participants. Completed in 1 December 2018.

Timeline

1 June 2015

Primary endpoint
30 June 2016

1 December 2018

Quick facts

Lead sponsor	University of Bergen
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	double
Primary purpose	treatment
Enrollment	20
Start date	1 June 2015
Primary completion	30 June 2016
Estimated completion	1 December 2018

Drugs / interventions tested

• Gracey curette.
• Ultrasonic scaler.
• Erythritol air-polishing.

Conditions studied

• Periodontitis — all drugs for Periodontitis →
• Adult Periodontitis — all drugs for Adult Periodontitis →

Sponsor

University of Bergen

Who can join

Adults 30 to 80, any sex, with Periodontitis or Adult Periodontitis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Background: To effectively disrupt microbial biofilm and remove dental calculus with minimal damage to the root surface and soft tissues with limited patient discomfort constitute a significant tenet of periodontal therapy. The aim of the present prospective 12-month study was to compare clinical and microbiological effects following an erythritol air-polishing vs. conventional mechanical debridement of furcation defects in a cohort of periodontal maintenance patients.

Methods: Twenty patients with grade II mandibular molar furcation defects volunteered to enroll in this study. In a split-mouth design, two furcation sites in each patient were randomly assigned to either receive subgingival debridement using erythritol air-polishing (test) or conventional ultrasonic/curette debridement (control) at baseline, and at 3, 6, 9 and 12 months. Probing depth, clinical attachment level and bleeding on probing were recorded at 3-month intervals. Subgingival microbiological samples obtained at baseline, 6 and 12 months were analyzed using checkerboard DNA-DNA hybridization. Discomfort from treatment was scored at 12 months using a visual analogue scale.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. A 12-month randomized controlled trial evaluating erythritol air-polishing versus curette/ultrasonic debridement of mandibular furcations in supportive periodontal therapy.
   Ulvik IM, Sæthre T, Bunæs DF, Lie SA, et al · · 2021 · cited 17× · PMID 33478480 · DOI 10.1186/s12903-021-01397-3