Last reviewed · How we verify
NCT04492748: RCCT
Rotator Cuff Tendinopathy Conservative Treatment With Collagen, PRP or Both
Phase 4 trial testing Collagen and platelet rich plasma (PRP) in Rotator Cuff Tendinosis in 90 participants. Status unknown.
30 September 2021
Quick facts
| Lead sponsor | Sutherland Medical Center |
|---|---|
| Phase | Phase 4 |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 90 |
| Start date | 1 July 2020 |
| Primary completion | 30 September 2021 |
| Estimated completion | 30 September 2021 |
| Sites | 1 location across Poland |
Drugs / interventions tested
- Collagen and platelet rich plasma (PRP)
- Collagen
- Platelet rich plasma (PRP) — full drug profile →
Conditions studied
- Rotator Cuff Tendinosis — all drugs for Rotator Cuff Tendinosis →
- Rotator Cuff Tears — all drugs for Rotator Cuff Tears →
Sponsor
Sutherland Medical Center
Who can join
18 and older, any sex, with Rotator Cuff Tendinosis or Rotator Cuff Tears. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of the trial is comparison of the effectiveness of three methods of conservative treatment in partial thickness rotator cuff injury (PTRCI): collagen with PRP injections, PRP injections alone and collagen injections alone.
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
Collagen and platelet-rich plasma in partial-thickness rotator cuff injuries. Friends or only indifferent neighbours? Randomised controlled trial.
Godek P, Szczepanowska-Wolowiec B, Golicki D. · · 2022 · cited 16× · PMID 36536333 · DOI 10.1186/s12891-022-06089-9 -
Regenerative Medicine Advancements: A Systematic Review on the Combinatory Effect of Platelet-Rich Plasma/Fibrin and Collagen.
Gallo N, Kodra C, Rocco D, Saponaro C, et al · · 2026 · PMID 41532141 · DOI 10.1155/ijbm/1679626 -
Collagen and PRP in Partial Thickness Rotator Cuff Injuries. Friends or Only Indifferent Neighbours? Randomized Controlled Trial
Godek P, Szczepanowska-Wolowiec B, Golicki D. · · 2021 · DOI 10.21203/rs.3.rs-770124/v1
Verify or expand the search:
- PubMed search for NCT04492748
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Rotator Cuff Tendinosis
Currently open trials in the same condition.
- NCT06095050 — Embolization Treatment of Chronic Refractory Shoulder Tendinopathy · NA · recruiting
- NCT06160427 — Connective Tissue Matrix for Rotator Cuff Tendinopathy · Phase 4 · active not recruiting
- NCT04923477 — Therapeutic Exercise for Rotator Cuff Tendinopathy / Subacromial Pain Syndrome - Outcomes and Mechanisms · NA · recruiting
Other Sutherland Medical Center trials
Trials by the same sponsor.
- NCT04734327 — Orthokine Therapy in Lumbar Degenerative Disease · Phase 4 · unknown
- NCT04492774 — Degenerative Lumbar Stenosis Conservative Treatment · Phase 4 · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04492748 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Sutherland Medical Center
- Last refreshed: 11 March 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04492748.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing