Who is sponsoring NCT04492540?

NCT04492540 is sponsored by Cairo University.

What drugs are being tested in NCT04492540?

Interventions in NCT04492540: aerobic exercise and MIND diet program, MIND diet program.

What condition does NCT04492540 study?

NCT04492540 studies Cognitive Decline, Postmenopausal Disorder.

Is NCT04492540 still recruiting?

NCT04492540 is currently completed. Last updated 6 October 2023.

Last reviewed 2023-10-06 · How we verify

NCT04492540

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Response of Sex Hormones and Different Functions to Exercise and Diet in Elderly Women

Completed NA Last updated 6 October 2023

What this trial tests

NA trial testing aerobic exercise and MIND diet program in Cognitive Decline in 60 participants. Completed in 30 September 2023.

Timeline

20 December 2020

Primary endpoint
30 September 2023

30 September 2023

Quick facts

Lead sponsor	Cairo University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	supportive care
Enrollment	60
Start date	20 December 2020
Primary completion	30 September 2023
Estimated completion	30 September 2023
Sites	1 location across Egypt

Drugs / interventions tested

aerobic exercise and MIND diet program
MIND diet program

Conditions studied

Cognitive Decline — all drugs for Cognitive Decline →
Postmenopausal Disorder — all drugs for Postmenopausal Disorder →

Sponsor

Cairo University

Who can join

Adults 60 to 70, female only, with Cognitive Decline or Postmenopausal Disorder. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

It is an interventional study in which 60 women estimated to enroll according to random allocation and divided into two groups. The study group will receive aerobic exercise in addition to diet restriction while the control group will receive diet recommendations. the aerobic exercise in form of treadmill training intensity of exercise moderate intensity, target heart rate (THR) will be 50-60% of heart maximum (HR MAX), time of session 40 min initial 10 min warm up exercise on treadmill in low intensity and active phase 20- 30 min intensity will increase until patient reach to THR then intensity decrease until session will be ended by cooling down phase for 10 min . The volunteers will perform exercise 3 times per week for 12 weeks .different functions and markers will be measured and sex hormones (estradiol ,testosterone. sex hormone binding globin ) pre and post

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Aerobic Exercise with Mediterranean-DASH Intervention for Neurodegenerative Delay Diet Promotes Brain Cells' Longevity despite Sex Hormone Deficiency in Postmenopausal Women: A Randomized Controlled Trial.
Elsayed MM, Rabiee A, El Refaye GE, Elsisi HF. · · 2022 · cited 10× · PMID 35419166 · DOI 10.1155/2022/4146742

Verify or expand the search:

Other recruiting trials for Cognitive Decline

Currently open trials in the same condition.

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NCT07399418 — TRIAD - Tracking Risk in Integrated Alzheimer's Diagnostics. · recruiting

Other Cairo University trials

Trials by the same sponsor.

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NCT07374575 — Egyptian Dental Professionals' Perspectives on the Oral Microbiome and Exosomes · not yet recruiting
NCT07381153 — In-Vitro Cytotoxicity Assessment of INOX (Nanoksa G Plus) Polymer Discs · not yet recruiting
NCT07375394 — 3D-Printed Extraoral Camera for Standardized Dental Photography · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04492540 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Cairo University
Last refreshed: 6 October 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04492540.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing