NCT04489095 is a NA clinical trial of Electrophysiology Study in Aortic Stenosis, sponsored by Henry Ford Health System.

Who is sponsoring NCT04489095?

NCT04489095 is sponsored by Henry Ford Health System.

What drugs are being tested in NCT04489095?

Interventions in NCT04489095: Electrophysiology Study.

What condition does NCT04489095 study?

NCT04489095 studies Aortic Stenosis, Heart Block, Aortic Insufficiency.

Is NCT04489095 still recruiting?

NCT04489095 is currently completed. Last updated 14 December 2022.

Last reviewed 2022-12-14 · How we verify

NCT04489095

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Conduction Disease After Transcatheter Aortic Valve Replacement

Completed NA Last updated 14 December 2022

What this trial tests

NA trial testing Electrophysiology Study in Aortic Stenosis in 126 participants. Completed in 1 August 2022.

Timeline

16 July 2020

Primary endpoint
17 February 2022

1 August 2022

Quick facts

Lead sponsor	Henry Ford Health System
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	diagnostic
Enrollment	126
Start date	16 July 2020
Primary completion	17 February 2022
Estimated completion	1 August 2022
Sites	1 location across United States

Drugs / interventions tested

Electrophysiology Study

Conditions studied

Aortic Stenosis — all drugs for Aortic Stenosis →
Heart Block — all drugs for Heart Block →
Aortic Insufficiency — all drugs for Aortic Insufficiency →

Sponsor

Henry Ford Health System — full company profile →

Who can join

18 and older, any sex, with Aortic Stenosis or Heart Block. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This is a prospective single center Cardiology department observational study. The study aim is to better understand the predictors of high grade conduction abnormalities associated with TAVR such that a more robust evidence-based and universal strategy to manage cardiac conduction disturbances in these patients, which has been elusive, can be developed.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Unmet Needs in TAVR: Conduction Disturbances and Management of Coronary Artery Disease.
Auffret V, Ridard C, Salerno N, Sorrentino S. · · 2022 · cited 7× · PMID 36362484 · DOI 10.3390/jcm11216256
Management of conduction disturbances after TAVI: the last step towards early discharge.
Muntané-Carol G, Romaguera R, Gómez-Hospital JA, Nuche J, et al · · 2025 · PMID 40607130 · DOI 10.26599/1671-5411.2025.05.004

Verify or expand the search:

Other recruiting trials for Aortic Stenosis

Currently open trials in the same condition.

NCT07197736 — DELINEATE-Prospective · recruiting
NCT07230964 — Correlation Between an Impedance Cardiography Test for Decompensation and the Development of Left Ventricular Replacemen · NA · recruiting
NCT07205068 — Improved Outcomes With Pre-Procedure Shockwave IVL of Common Femoral Artery Access Site Prior to Large Bore Access and P · NA · recruiting
NCT07052071 — Impact of Transcatheter Aortic Valve Implantation (TAVI) on the Gut Microbiota in Patients With Aortic Valve Stenosis · recruiting
NCT07144189 — AI Assessment of Low-Gradient Aortic Stenosis Severity Based on Echocardiography · recruiting

Other Henry Ford Health System trials

Trials by the same sponsor.

NCT07450183 — Perioperative Cemiplimab for Resectable Non-Small Cell Lung Cancer With High PD-L1 · Phase 2 · not yet recruiting
NCT07418853 — Comparison of Goniotomy Device Outcomes in Combined Phacoemulsification-goniotomy Surgeries · NA · not yet recruiting
NCT06670287 — The Use of Multiple Sensors to Track Sleep in Nightshift Workers · NA · recruiting
NCT07363525 — Michigan Initial Experience Using Tigertriever for Thrombectomy · not yet recruiting
NCT07530172 — Radioembolization Versus External Radiation Therapy · Phase 2 · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04489095 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Henry Ford Health System
Last refreshed: 14 December 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04489095.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing