NCT04488341

Effect of Aerobic Exercises on Sex Hormones and Coagulation Factors in Postmenopausal Elderly Women

Status unknown NA Last updated 11 August 2021

What this trial tests

NA trial testing aerobic exercises in addition to diet recommendations in Coagulation Disorder in 40 participants. Status unknown.

Timeline

20 September 2020

Primary endpoint
15 May 2022

20 August 2022

Quick facts

Lead sponsor	Cairo University
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	none
Primary purpose	prevention
Enrollment	40
Start date	20 September 2020
Primary completion	15 May 2022
Estimated completion	20 August 2022
Sites	1 location across Egypt

Drugs / interventions tested

• aerobic exercises in addition to diet recommendations
• diet recommendations

Conditions studied

• Coagulation Disorder — all drugs for Coagulation Disorder →

Sponsor

Cairo University

Who can join

Adults 60 to 70, female only, with Coagulation Disorder. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

PURPOSE:

to determine the effect of aerobic exercise training on sex hormones and coagulation factors in postmenopausal elderly women

BACKGROUND:

Cardiovascular disease (CVD) is the largest cause of death in women, and the risk of developing CVD increases after menopause . Because thrombosis is thought to be a cause of most acute cardiovascular events, abnormalities in endogenous coagulation and fibrinolysis may play an important role in the risk of an acute cardiovascular event. Aging is also associated with adverse changes in both coagulation and fibrinolysis. For instance, postmenopausal women exhibit higher fibrinogen levels and lower levels of endogenous fibrinolysis. Physical activity and physical fitness have consistently been linked to lower CVD rates in women. In fact, an inverse association between physical activity and total mortality, as well as a 50% reduction in risk of myocardial infarction, has been observed in physically active postmenopausal women. In addition to the numerous other benefits provided by regular physical activity, one of the mechanisms mediating the cardioprotective effect may be changes in the hemostatic system, particularly fibrinolysis

HYPOTHESES:

Aerobic exercises may have no effect on sex hormones and coagulation factors in elderly postmenopausal women

RESEARCH QUESTION:

Do aerobic exercises effect on sex hormones and coagulation factors in elderly postmenopausal women in response to exercises?

Publications & conference data

No peer-reviewed publications indexed yet for this trial.