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NCT04487639: FERTICOVID

Presence of SARS-CoV-2 (COVID-19) in Semen: Impact on Fertility Preservation in Male Oncological Patients ?

Completed NA Last updated 16 February 2024
What this trial tests

NA trial testing SARS-CoV-2 research in nasopharyngeal swab, sperm and serologics in Sperm Preservation in Oncological Patients in 129 participants. Completed in 31 December 2023.

Timeline
10 July 2020
Primary endpoint
2 July 2021
31 December 2023

Quick facts

Lead sponsorUniversity Hospital, Clermont-Ferrand
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationna
Designsingle group
Maskingnone
Primary purposediagnostic
Enrollment129
Start date10 July 2020
Primary completion2 July 2021
Estimated completion31 December 2023
Sites16 locations across France

Drugs / interventions tested

Conditions studied

Sponsor

University Hospital, Clermont-Ferrand

Who can join

Adults 18 to 60, male only, with Sperm Preservation in Oncological Patients or Fertility. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

During the COVID-19 pandemic, the French Agency of Biomedicine has recommended maintaining fertility preservation for patients requiring immediate oncological treatments exhibiting gonadotoxic effects. However, no study has examined the presence of SARS-CoV-2 in sperm from cancer patients. This study aims therefore to detect the presence of SARS-CoV-2, specifically in the seminal fluid and the spermatozoa fractions of cancer patient semen. The investigators will determine if the virus presence in sperm is associated with its presence in the nasal swabs, COVID symptoms, specific serological profiles and particular oncological pathologies/treatments.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. COVID-19 and Oncofertility: No SARS-CoV-2 in Semen but Inflammation Seems to Affect Sperm Parameters.
    Chaput L, Pons-Rejraji H, Chabrolles H, Fiot M, et al · · 2024 · cited 2× · PMID 39648939 · DOI 10.1002/jmv.70070

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Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04487639.

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