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NCT04487639: FERTICOVID
Presence of SARS-CoV-2 (COVID-19) in Semen: Impact on Fertility Preservation in Male Oncological Patients ?
NA trial testing SARS-CoV-2 research in nasopharyngeal swab, sperm and serologics in Sperm Preservation in Oncological Patients in 129 participants. Completed in 31 December 2023.
2 July 2021
Quick facts
| Lead sponsor | University Hospital, Clermont-Ferrand |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | diagnostic |
| Enrollment | 129 |
| Start date | 10 July 2020 |
| Primary completion | 2 July 2021 |
| Estimated completion | 31 December 2023 |
| Sites | 16 locations across France |
Drugs / interventions tested
- SARS-CoV-2 research in nasopharyngeal swab, sperm and serologics
Conditions studied
- Sperm Preservation in Oncological Patients — all drugs for Sperm Preservation in Oncological Patients →
- Fertility — all drugs for Fertility →
- Cryopreservation — all drugs for Cryopreservation →
Sponsor
University Hospital, Clermont-Ferrand
Who can join
Adults 18 to 60, male only, with Sperm Preservation in Oncological Patients or Fertility. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
During the COVID-19 pandemic, the French Agency of Biomedicine has recommended maintaining fertility preservation for patients requiring immediate oncological treatments exhibiting gonadotoxic effects. However, no study has examined the presence of SARS-CoV-2 in sperm from cancer patients. This study aims therefore to detect the presence of SARS-CoV-2, specifically in the seminal fluid and the spermatozoa fractions of cancer patient semen. The investigators will determine if the virus presence in sperm is associated with its presence in the nasal swabs, COVID symptoms, specific serological profiles and particular oncological pathologies/treatments.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
COVID-19 and Oncofertility: No SARS-CoV-2 in Semen but Inflammation Seems to Affect Sperm Parameters.
Chaput L, Pons-Rejraji H, Chabrolles H, Fiot M, et al · · 2024 · cited 2× · PMID 39648939 · DOI 10.1002/jmv.70070
Verify or expand the search:
- PubMed search for NCT04487639
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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- NCT07427537 — Exploration of Circulating microRNAs as Biomarkers of Chemo-induced Peripheral Neuropathy: a Study in Cancer Patients · NA · recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04487639 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Hospital, Clermont-Ferrand
- Last refreshed: 16 February 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04487639.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing