Last reviewed · How we verify
NCT04486573
Cardiac Effects From Radiation Therapy by MRI
NA trial testing Cardiac Magnetic Resonance Imaging in Radiation Treatment in 6 participants. Completed in 14 September 2023.
14 September 2023
Quick facts
| Lead sponsor | University of Colorado, Denver |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | diagnostic |
| Enrollment | 6 |
| Start date | 15 July 2020 |
| Primary completion | 14 September 2023 |
| Estimated completion | 14 September 2023 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Cardiac Magnetic Resonance Imaging
Conditions studied
- Radiation Treatment — all drugs for Radiation Treatment →
- Cancer — all drugs for Cancer →
- Cardiotoxicity — all drugs for Cardiotoxicity →
Sponsor
University of Colorado, Denver
Who can join
Adults 18 to 100, any sex, with Radiation Treatment or Cancer. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The investigators will identify 10 patients in the department of radiation oncology who will receive standard of-care radiation therapy, and the treating radiation oncologist anticipates a mean left ventricular dose of at least 5 Gy. Patients will be evaluated by CMRI before and within one week of the completion of RT. We will compare the pre- and post-RT CMRI scans to identify changes related to radiation exposure. Our primary endpoint will be changes in myocardial strain. Secondary endpoints will include other CMRI parameters.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Cardiovascular Magnetic Resonance Imaging in the Early Detection of Cardiotoxicity Induced by Cancer Therapies.
Wei X, Lin L, Zhang G, Zhou X. · · 2022 · cited 4× · PMID 36010197 · DOI 10.3390/diagnostics12081846
Verify or expand the search:
- PubMed search for NCT04486573
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Trials testing the same drug.
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- NCT04458883 — The Next Leap in Cardiac Magnetic Resonance Imaging:Cycling the Field · NA · recruiting
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Currently open trials in the same condition.
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Other University of Colorado, Denver trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04486573 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Colorado, Denver
- Last refreshed: 22 October 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04486573.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing