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NCT04477356
SU Versus GD for Sperm Preparation in IUI
NA trial testing SU in Infertility in 912 participants. Completed in 31 December 2023.
30 October 2023
Quick facts
| Lead sponsor | Mỹ Đức Hospital |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 912 |
| Start date | 10 August 2020 |
| Primary completion | 30 October 2023 |
| Estimated completion | 31 December 2023 |
| Sites | 1 location across Vietnam |
Drugs / interventions tested
- SU — full drug profile →
- DG
Conditions studied
- Infertility — all drugs for Infertility →
Sponsor
Mỹ Đức Hospital
Who can join
18 and older, female only, with Infertility. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Intrauterine insemination (IUI) is the first-line treatment for couples with unexplained and mild male factor infertility. The result of IUI depends on many factors including the sperm preparation techniques. Swim-up (SU) and Density Gradient (DG) are the two most commonly used techniques in sperm preparation for IUI. There is discussion about the effectiveness of these two techniques for IUI outcomes. The effectiveness of SU and DG methods on IUI success rate is not clearly understood and is controversial. This multicenter, randomized controlled trial will be conducted to determine which method (DG or SU) is better for IUI treatment.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Swim-up versus density gradients for sperm preparation in infertile couples undergoing intrauterine insemination: a randomized clinical trial.
Duong TND, Dang VQ, Le TK, Vu ATL, et al · · 2025 · cited 1× · PMID 40135621 · DOI 10.1093/humrep/deaf047
Verify or expand the search:
- PubMed search for NCT04477356
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other recruiting trials for Infertility
Currently open trials in the same condition.
- NCT07074015 — IntelliWell: An AI-Assisted Imaging Platform for Detection and Location of Ultra-Rare Testicular Sperm in Surgical Speci · NA · recruiting
- NCT07358468 — Impact Of FET Preparation Protocol On Endometrial Peristalsis: A Prospective Cohort Study · recruiting
- NCT07340827 — A Study to Compare the Efficacy and Safety of Follitropin Alfa/Lutropin Alfa Versus hMG in Japanese Participants With LH · Phase 3 · recruiting
- NCT07369362 — To Investigate if the Harvester® Improves Sperm Motility and Blastocyst Utilization (the Percent of Fertilized Eggs That · NA · active not recruiting
- NCT07153367 — Using a Fixed Dosage of Follitropin Delta for Ovarian Stimulation for Intrauterine Insemination: Rekovelle for Intrauter · Phase 2 · recruiting
Other Mỹ Đức Hospital trials
Trials by the same sponsor.
- NCT07358468 — Impact Of FET Preparation Protocol On Endometrial Peristalsis: A Prospective Cohort Study · recruiting
- NCT07197255 — Transcriptomic Profiling of Cumulus Cells From CAPA-IVM · recruiting
- NCT07171970 — IVM - Fresh ET (THE SAIGON PROTOCOL) Versus IVF - FET in PCOS Women · NA · recruiting
- NCT07088640 — Single Step Protocol and Multi-step Warming Protocol for Blastocyst FET · NA · recruiting
- NCT06934785 — LE + CC vs. LE for Ovulation Induction · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04477356 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Mỹ Đức Hospital
- Last refreshed: 1 February 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04477356.
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