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NCT04476069
Ibuprofen as a Pain Management in Pediatric Dentistry
Phase 3 trial testing IBUPROFEN in Pain Management in 56 participants. Completed in 30 May 2019.
28 March 2019
Quick facts
| Lead sponsor | Princess Nourah Bint Abdulrahman University |
|---|---|
| Phase | Phase 3 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | prevention |
| Enrollment | 56 |
| Start date | 10 January 2019 |
| Primary completion | 28 March 2019 |
| Estimated completion | 30 May 2019 |
| Sites | 1 location across Saudi Arabia |
Drugs / interventions tested
- IBUPROFEN (ibuprofen) — full drug profile →
Conditions studied
- Pain Management — all drugs for Pain Management →
Sponsor
Princess Nourah Bint Abdulrahman University
Who can join
Adults 5 to 13, any sex, with Pain Management. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Abstract Introduction: Administration of non-steroidal anti-inflammatory drugs (NSAIDs) before tooth extraction may reduce post-surgical pain, but there is a lack of research. Aims: To compare pain and anxiety in pediatric tooth extraction patients receiving a preoperative NSAID vs. placebo. Design: Randomized, double-blind, placebo-controlled clinical trial. Setting: Princess Nourah Bint Abdulrahman University's (PNU's) dental clinic in Riyadh, Saudi Arabia. Materials and Methods: Eligible pediatric tooth extraction patients were randomized to Group A, which received NSAID preoperatively, or Group B, which received placebo. Interventions: A research coordinator (RC) measured participants prior to extraction, and 3- and 24-hours post-extraction. Main Outcome Methods: The Wong-Baker FACES scale (WBFS) and the Modified Child Dental Anxiety Scale - Faces (MCDASf).
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Ibuprofen for acute postoperative pain in children.
Pessano S, Gloeck NR, Tancredi L, Ringsten M, et al · · 2024 · cited 7× · PMID 38180091 · DOI 10.1002/14651858.cd015432.pub2
Verify or expand the search:
- PubMed search for NCT04476069
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Pain Management
Currently open trials in the same condition.
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Other Princess Nourah Bint Abdulrahman University trials
Trials by the same sponsor.
- NCT07464691 — Effect of Prebiotics in Saudi Adults With Type 2 Diabetes · NA · not yet recruiting
- NCT07169292 — Effects of Wet-Cupping on Polycystic Ovary Syndrome Patients · NA · not yet recruiting
- NCT07410897 — Adapted Aquatic Exercise and Behavioral Outcomes, Flexibility, and Handgrip Strength in Children With Autism Spectrum Di · NA · completed
- NCT07270614 — Eight-week Sports Injury Prevention Program · NA · recruiting
- NCT07367607 — Circadian Modulation of Neurophysiological Responses to Therapeutic Massage Modalities · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04476069 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Princess Nourah Bint Abdulrahman University
- Last refreshed: 17 July 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04476069.
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